ArticleInternational journal of clinical and experimental pathology2015
High prevalence of maternal vitamin D deficiency in preterm births in northeast China, Shenyang.
Article in International journal of clinical and experimental pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
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The trial behind it
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Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Effect of maternal vitamin D status on risk of adverse birth outcomes: a systematic review and dose-response meta-analysis of observational studies.European journal of nutrition · 2022Pooled it
- Pooled it
- Does Maternal Vitamin D Deficiency Increase the Risk of Preterm Birth: A Meta-Analysis of Observational Studies.Nutrients · 2016Pooled it
- Transcriptome analysis of early pregnancy vitamin D status and spontaneous preterm birth.PloS one · 2020Trial
- Maternal serum concentrations of vitamin D in pregnancy and preterm birth: a case-control study in Southern Sweden.European journal of nutrition · 2025Article
- The role of human milk nutrients in preventing necrotizing enterocolitis.Frontiers in pediatrics · 2023Review
- Serum 25-Hydroxyvitamin D Levels in Type 2 Diabetes Patients in North China: Seasonality and the Association between Vitamin D Status and Glycosylated Hemoglobin Levels.International journal of clinical practice · 2023Article
- Article
- Vitamin D status in women with dichorionic twin pregnancies and their neonates: a pilot study in China.BMC pregnancy and childbirth · 2021Observational
- Article
- Prevalence of vitamin D deficiency in the pregnant women: an observational study in Shanghai, China.Archives of public health = Archives belges de sante publique · 2020Article
- Maternal serum vitamin D levels and preterm delivery among low-risk parturients in Lagos, Nigeria.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2019Article
- Vitamin D ameliorates neonatal necrotizing enterocolitis via suppressing TLR4 in a murine model.Pediatric research · 2018Article
- Influent factors of gestational vitamin D deficiency and its relation to an increased risk of preterm delivery in Chinese population.Scientific reports · 2018Article
- Maternal vitamin D deficiency increases the risk of adverse neonatal outcomes in the Chinese population: A prospective cohort study.PloS one · 2018Article
- Severe Vitamin D Deficiency in Human Immunodeficiency Virus-Infected Pregnant Women is Associated with Preterm Birth.American journal of perinatology · 2017Article
- Maternal Vitamin D Status in the Late Second Trimester and the Risk of Severe Preeclampsia in Southeastern China.Nutrients · 2017Article
- Prevalence of Vitamin D Deficiency in Burka-clad Pregnant Women in a 450-Bedded Maternity Hospital of Delhi.Journal of obstetrics and gynaecology of India · 2016Article
- Review
- Preconception Care: A New Standard of Care within Maternal Health Services.BioMed research international · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionMaternal vitamin D deficiency has been associated with a number of fetal and neonatal health problems. Preterm birth is one of the most detrimental, and the role of maternal vitamin D deficiency in preterm births has not been universally acknowledged. There had been limited epidemiological studies of vitamin D deficiency on the Chinese population. SUBJECTS AND
methods1103 women delivered in Shengjing Hospital, China Medical University from January 1(st), 2012 to January 1(st), 2013. Finally, 821 mother-newborn pairs which contained 143 mother-newborn pairs who were preterm delivery were recruited for analysis.
resultsThere was significant difference between spring and summer (P<0.0001) as well as spring and autumn (P<0.01). Compared to those in summer and autumn, the 25 (OH) D level was significantly lower in winter (summer vs winter P<0.0001, autumn vs winter P<0.0001). Maternal vitamin D level showed obvious variation with months and seasons, with higher level in summer months and lower level in winter months. There were significant difference between the vitamin D level of the very preterm group and the mildly preterm groups (P<0.01), as well as the very preterm group and the in-term groups (P<0.001). Prevalence of Vitamin D deficiency occurred in 63.04% of pregnant women in very preterm group, compared with 36.61% in in-term group.
conclusionVitamin D nutritional status of pregnant women and their newborns in Shenyang were relatively good compared to cities in similar latitudes. Vitamin D deficiency was most severe in late spring and least in summer. Severe preterm births before 31 weeks of gestation was associated with maternal vitamin D deficiency.
Indexed as
Identifiers
25973031PMC4396334W2415829987What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.