Evidence map›Paper›PMID 25972712›Full record

ArticleJournal of craniovertebral junction & spine

The impact of L5 dorsal root ganglion degeneration and Adamkiewicz artery vasospasm on descending colon dilatation following spinal subarachnoid hemorrhage: An experimental study; first report.

Cengiz Ozturk, Ayhan Kanat, Mehmet Dumlu Aydin, Coskun Yolas, Mehmet Esref Kabalar, Betul Gundogdu, Aslihan Duman, Ilyas Ferit Kanat, Cemal Gundogdu

Open access · diamondAbstract read
In one paragraph

Article in Journal of craniovertebral junction & spine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Cengiz OzturkErzurum Regional Research and Education Hospital Family Physician, Erzurum, Turkey.
Ayhan KanatDepartment of Neurosurgery, Medical Faculty, Recep Tayyip Erdogan University, Rize, Turkey.
Mehmet Dumlu AydinDepartment of Neurosurgery, Medical Faculty, Ataturk University, Erzurum, Turkey.
Coskun YolasDepartment of Neurosurgery, Erzurum Regional Research and Education Hospital Family Physician, Erzurum, Turkey.
Mehmet Esref KabalarDepartment of Pathology, Erzurum Regional Research and Education Hospital Family Physician, Erzurum, Turkey.
Betul GundogduDepartment of Pathology, Medical Faculty, Ataturk University, Erzurum, Turkey.
Aslihan DumanDepartment of Pathology, Giresun University, Medical Faculty, Giresun, Turkey.
Ilyas Ferit KanatDepartment of Internal Medicine, Atatürk Training and Research Hospital, Ankara, Turkey.
Cemal GundogduDepartment of Pathology, Medical Faculty, Ataturk University, Erzurum, Turkey.
Atatürk University · TRErzurum Regional Training and Research Hospital · TRGiresun University · TRRecep Tayyip Erdoğan University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextSomato-sensitive innervation of bowels are maintained by lower segments of spinal cord and the blood supply of the lower spinal cord is heavily dependent on Adamkiewicz artery. Although bowel problems are sometimes seen in subarachnoid hemorrhage neither Adamkiewicz artery spasm nor spinal cord ischemia has not been elucidated as a cause of bowel dilatation so far.

aimsThe goal of this study was to study the effects Adamkiewicz artery (AKA) vasospasm in lumbar subarachnoid hemorrhage (SAH) on bowel dilatation severity. SETTINGS AND

designAn experimental rabbit study. MATERIALS AND

methodsThe study was conducted on 25 rabbits, which were randomly divided into three groups: Spinal SAH (N = 13), serum saline (SS) (SS; N = 7) and control (N = 5) groups. Experimental spinal SAH was performed. After 21 days, volume values of descending parts of large bowels and degenerated neuron density of L5DRG were analyzed. STATISTICAL ANALYSIS USED: Statistical analysis was performed using the PASW Statistics 18.0 for Windows (SPSS Inc., Chicago, Illinois). Two-tailed t-test and Mann-Whitney U-tests were used. The statistical significance was set at P < 0.05.

resultsThe mean volume of imaginary descending colons was estimated as 93 ± 12 cm(3) in the control group and 121 ± 26 cm(3) in the SS group and 176 ± 49 cm(3) in SAH group. Volume augmentations of the descending colons and degenerated neuron density L5DRG were significantly different between the SAH and other two groups (P < 0.05).

conclusionAn inverse relationship between the living neuronal density of the L5DRG and the volume of imaginary descending colon values was occurred. Our findings will aid in the planning of future experimental studies and determining the clinical relevance on such studies.

Indexed as

Adamkiewicz arterybowel dilatationdorsal root ganglionlumbarspinesubarachnoid hemorrhagevasospasm

Identifiers

PMID25972712
PMCPMC4426525
OpenAlexW2085927529

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.