Evidence map›Paper›PMID 25972505›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2015

The Transition From Postexposure Prophylaxis to Preexposure Prophylaxis: An Emerging Opportunity for Biobehavioral HIV Prevention.

Sachin Jain, Douglas S Krakower, Kenneth H Mayer

Open access · bronzeAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Observational
  4. Observational
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. PrEP Continuation, HIV and STI Testing Rates, and Delivery of Preventive Care in a Clinic-Based Cohort.AIDS education and prevention : official publication of the International Society for AIDS Education · 2018
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Sachin JainMontefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York.
Douglas S KrakowerBeth Israel Deaconess Medical Center, Harvard Medical School The Fenway Institute, Fenway Health, Boston, Massachusetts.
Kenneth H MayerBeth Israel Deaconess Medical Center, Harvard Medical School The Fenway Institute, Fenway Health, Boston, Massachusetts.
Hadassah Medical Center · ILAlbert Einstein College of Medicine · US

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ROBERT A. PARKER · 2004 to 2026
$94.4M
Optimizing HIV Pre-Exposure Prophylaxis through Shared Decision MakingK23MH098795 · NIMH · BETH ISRAEL DEACONESS MEDICAL CENTER · PI KRAKOWER, DOUGLAS SCOTT · 2012 to 2016
$873k
NIAID NIH HHS P30 AI060354NIMH NIH HHS K23 MH098795
6 · The paper itself

Abstract

Although some individuals who present for antiretroviral postexposure prophylaxis (PEP) had a 1-time exposure to human immunodeficiency virus (HIV), others may be recurrently risky. Given that preexposure prophylaxis (PrEP) has been shown to be efficacious, identification of those individuals who present for PEP who might benefit from PrEP is important to decrease HIV acquisition in high-risk individuals. While inclusion criteria for PrEP have been developed, there is a paucity of data to help clinicians determine which PEP users are at highest risk for HIV acquisition and therefore should be offered PrEP. We will discuss the rationale for using PrEP after PEP use, and will focus on the assessment of PEP users who may benefit from PrEP.

Indexed as

Post-Exposure ProphylaxisPre-Exposure ProphylaxisAnti-HIV AgentsHIV InfectionsHumansRisk Reduction BehaviorAnti-HIV AgentsHIV preventionpostexposure prophylaxispreexposure prophylaxis

Identifiers

PMID25972505
PMCPMC4492410
OpenAlexW1917082131

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.