Evidence map›Paper›PMID 25972443›Full record

ArticleArchives of disease in childhood. Fetal and neonatal edition2015

Cause-specific neonatal mortality: analysis of 3772 neonatal deaths in Nepal, Bangladesh, Malawi and India.

Edward Fottrell, David Osrin, Glyn Alcock, Kishwar Azad, Ujwala Bapat, James Beard, Austin Bondo, Tim Colbourn, Sushmita Das, Carina King and 17 more

Open access · hybridAbstract read
In one paragraph

Article in Archives of disease in childhood. Fetal and neonatal edition, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
9.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 66 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

27 authors at 6 institutions in 4 countries.

Edward FottrellUniversity College London, Institute for Global Health, London, UK.
David OsrinUniversity College London, Institute for Global Health, London, UK.
Glyn AlcockUniversity College London, Institute for Global Health, London, UK.
Kishwar AzadDiabetic Association of Bangladesh, Perinatal Care Project, Dhaka, Bangladesh.
Ujwala BapatSociety for Nutrition, Education and Health Action, Mumbai, India.
James BeardUniversity College London, Institute for Global Health, London, UK.
Austin BondoParent and Child Health Initiative, Lilongwe, Malawi.
Tim ColbournUniversity College London, Institute for Global Health, London, UK.
Sushmita DasSociety for Nutrition, Education and Health Action, Mumbai, India.
Carina KingUniversity College London, Institute for Global Health, London, UK.
Dharma ManandharMother and Infant Research Activities, Kathmandu, Nepal.
Sunil ManandharMother and Infant Research Activities, Kathmandu, Nepal.
Joanna MorrisonUniversity College London, Institute for Global Health, London, UK.
Charles MwansamboMinistry of Health, Government of Malawi, Lilongwe, Malawi.
Nirmala NairEkjut, Chakradharpur, India.
Bejoy NambiarUniversity College London, Institute for Global Health, London, UK.
Melissa NeumanUniversity College London, Institute for Global Health, London, UK.
Tambosi PhiriMaiMwana Project, Mchinji, Malawi.
Naomi SavilleUniversity College London, Institute for Global Health, London, UK.
Aman SenMother and Infant Research Activities, Kathmandu, Nepal.
Nadine SewardUniversity College London, Institute for Global Health, London, UK.
Neena Shah MooreSociety for Nutrition, Education and Health Action, Mumbai, India.
Bhim Prasad ShresthaMother and Infant Research Activities, Kathmandu, Nepal.
Bright SinginiMaiMwana Project, Mchinji, Malawi.
Kirti Man TumbahangpheMother and Infant Research Activities, Kathmandu, Nepal.
Anthony CostelloUniversity College London, Institute for Global Health, London, UK.
Audrey ProstUniversity College London, Institute for Global Health, London, UK.
University College London · GBMother and Infant Research Activities · NPSociety for Nutrition Education and Health Action · INEkjut · INMinistry of Health · MWPublic Health Institute of Malawi · MW

Funding

Wellcome Trust 085417ma/Z/08/ZWellcome Trust 091561Wellcome Trust 100714
6 · The paper itself

Abstract

objectiveUnderstanding the causes of death is key to tackling the burden of three million annual neonatal deaths. Resource-poor settings lack effective vital registration systems for births, deaths and causes of death. We set out to describe cause-specific neonatal mortality in rural areas of Malawi, Bangladesh, Nepal and rural and urban India using verbal autopsy (VA) data.

designWe prospectively recorded births, neonatal deaths and stillbirths in seven population surveillance sites. VAs were carried out to ascertain cause of death. We applied descriptive epidemiological techniques and the InterVA method to characterise the burden, timing and causes of neonatal mortality at each site.

resultsAnalysis included 3772 neonatal deaths and 3256 stillbirths. Between 63% and 82% of neonatal deaths occurred in the first week of life, and males were more likely to die than females. Prematurity, birth asphyxia and infections accounted for most neonatal deaths, but important subnational and regional differences were observed. More than one-third of deaths in urban India were attributed to asphyxia, making it the leading cause of death in this setting.

conclusionsPopulation-based VA methods can fill information gaps on the burden and causes of neonatal mortality in resource-poor and data-poor settings. Local data should be used to inform and monitor the implementation of interventions to improve newborn health. High rates of home births demand a particular focus on community interventions to improve hygienic delivery and essential newborn care.

Indexed as

Cause of DeathInfant MortalityAutopsyBangladeshFemaleHumansIndiaInfantMalawiMaleNepalPopulation SurveillanceProspective StudiesSex DistributionData CollectionEpidemiologyMeasurementMortalityNeonatology

Identifiers

PMID25972443
PMCPMC4552925
OpenAlexW2162677037

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.