Evidence map›Paper›PMID 25972415›Full record

ArticleJournal of clinical microbiology2015

Use of the FilmArray System for Detection of Zaire ebolavirus in a Small Hospital in Bo, Sierra Leone.

Tomasz A Leski, Rashid Ansumana, Chris R Taitt, Joseph M Lamin, Umaru Bangura, Joseph Lahai, George Mbayo, Mohamed B Kanneh, Ben Bawo, Alfred S Bockarie and 5 more

Registry-linked trialAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02658331 (Clinical Evaluation of the BioFire FilmArray® BioThreat-E Test for the Diagnosis of Ebola Virus Disease in West Africa), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02658331 completednot on this map

Clinical Evaluation of the BioFire FilmArray® BioThreat-E Test for the Diagnosis of Ebola Virus Disease in West Africa

TypeobservationalSponsorBioMérieuxRan2015 to 2015Enrolled156ConditionsEbola Virus Disease
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. The current landscape of nucleic acid tests for filovirus detection.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2018
    Review
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Tomasz A LeskiNaval Research Laboratory, Washington, DC, USA tomasz.leski@nrl.navy.mil.ORCID http://orcid.org/0000-0001-7688-9887
Rashid AnsumanaMercy Hospital Research Laboratory, Bo, Sierra Leone Njala University, Njala, Sierra Leone Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Chris R TaittNaval Research Laboratory, Washington, DC, USA.
Joseph M LaminMercy Hospital Research Laboratory, Bo, Sierra Leone.
Umaru BanguraMercy Hospital Research Laboratory, Bo, Sierra Leone.
Joseph LahaiMercy Hospital Research Laboratory, Bo, Sierra Leone.
George MbayoMercy Hospital, Bo, Sierra Leone.
Mohamed B KannehMercy Hospital, Bo, Sierra Leone.
Ben BawoMercy Hospital, Bo, Sierra Leone.
Alfred S BockarieMercy Hospital Research Laboratory, Bo, Sierra Leone.
Matt ScullionBioFire Defense LLC, Salt Lake City, Utah, USA.
Cynthia L PhillipsBioFire Defense LLC, Salt Lake City, Utah, USA.
Cynthia P HornerMercy Hospital, Bo, Sierra Leone.
Kathryn H JacobsenGeorge Mason University, Fairfax, Virginia, USA.
David A StengerNaval Research Laboratory, Washington, DC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Laboratories associated with small hospitals often have limited expertise, personnel, and equipment to rapidly identify rare and emerging infectious diseases. We describe the successful use of the FilmArray system for rapid detection of Ebola virus directly from clinical samples in 6 out of 83 tested subjects in a small health care center in Sierra Leone.

Indexed as

BloodEbolavirusHemorrhagic Fever, EbolaHospitalsHumansMolecular Diagnostic TechniquesMultiplex Polymerase Chain ReactionPharynxSierra LeoneVirology

Identifiers

PMID25972415
PMCPMC4473222

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.