Evidence map›Paper›PMID 25972238›Full record

SynthesisMolecular neurobiology2016

Hyperglycemia and Mortality Risk in Patients with Primary Intracerebral Hemorrhage: A Meta-Analysis.

Xiaoming Guo, Helin Li, Zhiwen Zhang, Shouchun Li, Lizhi Zhang, Jiajing Zhang, Guiqing Han

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Molecular neurobiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Hemoglobin glycation index predicts mortality in intracerebral hemorrhage: a nonlinear threshold effect.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaoming GuoNeurosurgery Department, The First Affiliated Hospital of General Hospital of PLA, Beijing, 100048, China. guoqzgz@sina.cn.
Helin LiNeurology Department, The First Affiliated Hospital of General Hospital of PLA, Beijing, 100048, China.
Zhiwen ZhangNeurosurgery Department, The First Affiliated Hospital of General Hospital of PLA, Beijing, 100048, China.
Shouchun LiNeurosurgery Department, The First Affiliated Hospital of General Hospital of PLA, Beijing, 100048, China.
Lizhi ZhangNeurosurgery Department, The First Affiliated Hospital of General Hospital of PLA, Beijing, 100048, China.
Jiajing ZhangNeurosurgery Department, Air Force General Hospital of PLA, Beijing, 100048, China.
Guiqing HanDepartment of Medicine, Guizhou Hospital, Guiyang, 550002, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperglycemia may be associated with worse functional outcomes in patients with primary intracerebral hemorrhage. We performed a systematic review and meta-analysis to investigate the relationship between hyperglycemia and mortality risk in patients with primary intracerebral hemorrhage. We searched PubMed and Embase databases for studies investigating the association between hyperglycemia and mortality risk in patients with primary intracerebral hemorrhage. We estimated the pooled relative risk (RR) with its 95% confidence interval (95% CI) to assess the impact of hyperglycemia on mortality risk. Seventeen studies with a total of 6527 primary intracerebral hemorrhage patients were included. Meta-analysis of those studies showed that hyperglycemia significantly increased risk of mortality in patients with primary intracerebral hemorrhage (RR = 2.36, 95% CI 1.79-3.12). Subgroup analysis by time of follow-up showed that hyperglycemia significantly increased risk of short-term mortality (RR = 3.97, 95% CI 2.13-7.43) and long-term mortality (RR = 1.53, 95% CI 1.14-2.05). The RR of mortality for per 1-mmol/L increment in glucose level was 1.14 (95% CI 1.06-1.22). In patients with primary intracerebral hemorrhage, hyperglycemia significantly increases risk of both short-term mortality and long-term mortality.

Indexed as

Cerebral HemorrhageGlucoseHumansHyperglycemiaPublication BiasRiskRisk FactorsGlucoseHemorrhagic strokeHyperglycemiaMortality

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.