ArticleIntensive care medicine2015
Acute kidney injury after out-of-hospital cardiac arrest: risk factors and prognosis in a large cohort.
Article in Intensive care medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
57 citing papers in PubMed, 2 syntheses or guidelines pooled it, 139 citations in OpenAlex.
- European Resuscitation Council and European Society of Intensive Care Medicine guidelines 2025: post-resuscitation care.Intensive care medicine · 2025Guideline
- Sex differences in survival after out-of-hospital cardiac arrest: a meta-analysis.Critical care (London, England) · 2020Pooled it
- Acute kidney injury after in-hospital cardiac arrest.Resuscitation · 2021Trial
- Acute kidney injury after out of hospital pediatric cardiac arrest.Resuscitation · 2018Trial
- Development and validation of machine learning models to predict 30-day mortality in patients with cardiac arrest complicated by acute kidney injury.Clinics (Sao Paulo, Brazil) · 2026Article
- Development of a Clinical Prediction Model for Acute Kidney Injury Among In-Hospital Cardiac Arrest Patients During Intensive Care Unit Hospitalization.Reviews in cardiovascular medicine · 2026Article
- Integrated transcriptomics identifies ER stress-associated apoptosis in post-resuscitation AKI and supports early Dl-3-n-butylphthalide-associated renoprotection in a porcine TCA model.Frontiers in pharmacology · 2026Article
- Dual-phase CT radiomics for acute kidney injury prediction after out-of-hospital cardiac arrest.Frontiers in radiology · 2026Article
- Impact of Hypothermic Temperature Control on Plasma and Soft Tissue Pharmacokinetics of Penicillin/Beta-Lactamase Inhibitor Combinations in Patients Resuscitated After Cardiac Arrest.Clinical pharmacokinetics · 2025Article
- Renal function and clinical outcomes in survivors of out-of-hospital cardiac arrest.Resuscitation plus · 2025Article
- Acute Kidney Injury in Patients After Cardiac Arrest: Effects of Targeted Temperature Management.Life (Basel, Switzerland) · 2025Article
- A machine learning model for prediction of cardiac arrest-associated acute kidney injury in the ICU: an internal and external validation study.Frontiers in medicine · 2025Article
- Preexisting hemodialysis and survival outcome in out-of-hospital cardiac arrest patients: Ulsan, South Korea.Frontiers in medicine · 2025Article
- Chinese clinical practice consensus for device-supported treatment in adults with post-cardiac arrest syndrome (2024 Edition).World journal of emergency medicine · 2025Article
- Acute Kidney Injury in Deceased Organ Donors: Risk Factors And Impacts on Transplantation Outcomes.Transplantation direct · 2024Article
- Intensive care unit cardiac arrest among very elderly critically ill patients - is cardiopulmonary resuscitation justified?Scandinavian journal of trauma, resuscitation and emergency medicine · 2024Article
- Extracerebral multiple organ dysfunction and interactions with brain injury after cardiac arrest.Resuscitation plus · 2024Review
- Article
- Impact of arginine-vasopressin on regional perfusions in a porcine model of post-resuscitation syndrome.Resuscitation plus · 2024Article
- Post Cardiac Arrest Care in the Cardiac Intensive Care Unit.Current cardiology reports · 2024Review
Corrections and comments
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Authors and funding
11 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeCharacteristics of acute kidney injury (AKI) occurring after out-of-hospital cardiac arrest (OHCA) are incompletely described. We aimed to evaluate the prevalence of AKI, identifying risk factors and assessing the impact of AKI on outcome after OHCA.
methodsSingle-center study between 2007 and 2012 in a cardiac arrest center in Paris, France. All consecutive OHCA patients with at least one weight measurement and one serum creatinine level available and treated by therapeutic hypothermia were included, except those with chronic kidney disease and those dead on arrival. AKI was defined as stage 3 of the Acute Kidney Injury Network (AKIN) classification. Main outcome was day-30 mortality. Factors associated with AKI occurrence and day-30 mortality were evaluated by logistic regression.
results580 patients (71.3% male, median age 59.3 years, initial shockable rhythm in 56.9% of cases) were included in the analysis. AKI stage 3 occurred in 280 (48.3%) patients. Age, male gender, resuscitation duration, post-resuscitation shock, public setting, and initial rhythm were associated with AKI stage 3. AKI stage 3 was associated with a significantly higher day-30 mortality rate [OR 1.60; 95% CI (1.05, 2.43); p = 0.03]. No independent association between AKI and neurologic outcome was observed. At day 30, 67 patients had a normal kidney function (eGFR >75 mL/min/1.73 m(2)), and five remained dialysis-dependent. Patients with eGFR higher than 75 mL/min/1.73 m(2) at day 30 were younger and more frequently male.
conclusionAKI stage 3 was frequent after OHCA and was associated with poorer outcome. Improvement strategies in post-resuscitation care should consider AKI as a potential target of treatment.
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