Evidence map›Paper›PMID 25971213›Full record

ReviewSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2015

The role of physical rehabilitation in stem cell transplantation patients.

Amir Steinberg, Arash Asher, Charlotte Bailey, Jack B Fu

6 registry-linked trialsOpen access · greenAbstract readReview
In one paragraph

Review in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 6 registered trials, which are not on this map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03699358 completednot on this map

Does Myeloid or Lymphoid Origin of Hematologic Neoplasm Affect Pulmonary Functions, Muscle Strength, Exercise Capacity, Fatigue and Quality of Life?

TypeobservationalSponsorGazi UniversityRan2012 to 2017Enrolled57ConditionsStem Cell Transplantation
NCT03915249 completednot on this mapstarted 2017, after this paper: background citation

Investigation of Relationship Among Physical Activity, Pulmonary Functions and Physical Functions in Candidates With Allogeneic Hematopoietic Stem Cell Transplantation: a Cross Sectional Study

TypeobservationalSponsorGazi UniversityRan2017 to 2019Enrolled49ConditionsStem Cell Transplantation
NCT05154305 narecruitingnot on this mapstarted 2019, after this paper: background citation

Multidisciplinary Rehabilitation of Children and Adolescents After Acute Cancer Treatment

TypeinterventionalSponsorUniversity Hospital, GhentRan2019 to 2026Enrolled60ConditionsCancer Survivors, Rehabilitation, Exercise TherapyArmsmultidisciplinary intervention
NCT06134297 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Adherence, Feasibility, Clinical Evolution Therapeutic Efficacy of Three Different Muscle Overload Models Used for Physical Rehabilitation of Patients Undergoing Bone Marrow Transplantation: a Randomized Clinical Trial

TypeinterventionalSponsorFederal University of Health Science of Porto AlegreRan2022 to 2024Enrolled93ConditionsStem Cell TransplantationArmsCycle ergometer, Strength Training - elastic band and shin guards, Cycle ergometer, elastic band and shin guards
NCT06953648 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Remotely Monitored, Mobile Health-supported, High Intensity Interval Training Before Hematopoietic Stem Cell Transplantation (REMM-HIIT-HCT)

TypeinterventionalSponsorUniversity of Kansas Medical CenterRan2025 to 2030Enrolled126ConditionsHematopoietic Stem Cell Transplantation, Cardiorespiratory FitnessArmsHigh Intensity Interval Training
NCT07516314 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

ACT to Reduce Morbidity and Mortality in Hematopoietic Stem Cell Transplant (HCT) Patients (ACTivate)

TypeinterventionalSponsorAnthony Sung, MDRan2026 to 2031Enrolled476ConditionsStem Cell Transplant PatientsArmsACTivate sessions
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 60 citations in OpenAlex.

  1. Prehabilitation to improve function after autologous stem cell transplantation: A pilot randomized controlled trial (PIRATE).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Trial
  2. Trial
  3. Safety and feasibility of electrical muscle stimulation in patients undergoing autologous and allogeneic stem cell transplantation or intensive chemotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019
    Trial
  4. Trial
  5. Review
  6. Article
  7. Participation in life activities after hematopoietic cell transplantation in older adults.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  8. Article
  9. Article
  10. Sequestration of Inflammation in Parkinson's Disease via Stem Cell Therapy.International journal of molecular sciences · 2022
    Review
  11. Article
  12. Article
  13. Article
  14. Effects of partly supervised and home-based exercise program in patients undergoing hematopoietic stem cell transplantation: a case-control study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Article
  15. Factors affecting lower limb muscle strength and cardiopulmonary fitness after allogeneic hematopoietic stem cell transplantation.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019
    Article
  16. Article
  17. Article
  18. A hospital and home-based exercise program to address functional decline in people following allogeneic stem cell transplantation.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Amir SteinbergBlood and Marrow Transplantation, Mount Sinai Hospital, 1 Gustave Levy Place, MB 1410, New York City, NY, 10029, USA, amir.steinberg@mountsinai.org.
Arash Asher
Charlotte Bailey
Jack B Fu
Cedars-Sinai Medical Center · USMount Sinai Hospital · USThe University of Texas MD Anderson Cancer Center · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

The purpose of this paper is to review the evidence for the role of physical rehabilitation in stem cell transplantation patients. We will also review the literature and discuss professional experiences on how rehabilitation can play a role in stem cell transplant care and survivorship. Hematopoietic stem cell transplantation (HCT) is a procedure that has evolved substantially over the years to help treat multiple conditions, particularly hematologic malignancies. HCT can be very stressful on the body and can leave patients weakened and sometimes quite debilitated. Supportive care measures have advanced to improve the quality of life and overall survival of HCT survivors. One key component of improved supportive care is gaining increased attention, and that is physical medicine and rehabilitation. Its role in HCT survivorship care is expanding, and new insight and research within the discipline have focused on fatigue, inflammation, exercise, and the development of structured rehabilitation programs to improve the musculoskeletal sequelae of transplantation. This literature review has demonstrated the utility of physical rehabilitation in HCT, its impact on cancer-related fatigue, and to outline the current state of the literature on these topics. The paper delves into a background of HCT. Cancer-related fatigue in HCT is then discussed and summarized, and the role that exercise plays in modifying such fatigue is outlined. We then outline the models and the impact that physical rehabilitation may play in HCT recipients.

Indexed as

FatigueHematopoietic Stem Cell TransplantationHumansPhysical Therapy ModalitiesQuality of LifeStem Cell TransplantationSurvivors

Identifiers

PMID25971213
PMCPMC4703401
OpenAlexW2163102543

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.