Evidence map›Paper›PMID 25970587›Full record

ReviewBiomolecules2015

Structural biology of bacterial RNA polymerase.

Katsuhiko S Murakami

Abstract readReview
In one paragraph

Review in Biomolecules, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed.

  1. Dissection ofmBio · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Virulence Regulation inMicroorganisms · 2025
    Review
  8. Quorum Sensing inMicroorganisms · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Investigation of Multi-SubunitInternational journal of molecular sciences · 2023
    Article
  18. Chitosan loaded RNA polymerase inhibitor nanoparticles increased attenuation in toxin release fromSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
  19. σMicrobiology spectrum · 2022
    Article
  20. Life (Basel, Switzerland) · 2022
    Review

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Katsuhiko S MurakamiDepartment of Biochemistry and Molecular Biology, The Center for RNA Molecular Biology, The Pennsylvania State University, University Park, PA 16802, USA. kum14@psu.edu.

Funding

X-Ray Crystallographic Studies of Multi-Subunit Nucleic Acid PolymerasesR01GM087350 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI MURAKAMI, KATSUHIKO · 2010 to 2018
$2.6M
NIGMS NIH HHS GM087350NIGMS NIH HHS R01 GM087350
6 · The paper itself

Abstract

Since its discovery and characterization in the early 1960s (Hurwitz, J. The discovery of RNA polymerase. J. Biol. Chem. 2005, 280, 42477-42485), an enormous amount of biochemical, biophysical and genetic data has been collected on bacterial RNA polymerase (RNAP). In the late 1990s, structural information pertaining to bacterial RNAP has emerged that provided unprecedented insights into the function and mechanism of RNA transcription. In this review, I list all structures related to bacterial RNAP (as determined by X-ray crystallography and NMR methods available from the Protein Data Bank), describe their contributions to bacterial transcription research and discuss the role that small molecules play in inhibiting bacterial RNA transcription.

Indexed as

Amino Acid SequenceBacterial ProteinsDNA-Directed RNA PolymerasesEnzyme InhibitorsMolecular Sequence DataBacterial ProteinsDNA-Directed RNA PolymerasesEnzyme Inhibitorsanti-σ factorbacterial RNA polymerasecore enzymeholoenzymeinhibitor antibioticNMRtranscriptiontranscription factorX-ray crystallographyσ factor

Identifiers

PMID25970587
PMCPMC4496699

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.