ReviewWiley interdisciplinary reviews. Developmental biology
Salivary gland development and disease.
Review in Wiley interdisciplinary reviews. Developmental biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 59 citations in OpenAlex.
- An NKX2-3/5/6 homolog is required downstream of BMP signaling to pattern the sensory-adhesive organ of a tunicate larva.PLoS genetics · 2026Article
- Porcine submandibular glands as potential salivary gland experimental models: histological, immunohistochemical, and ultrastructural characterization.Journal of molecular histology · 2026Article
- A Mouthful of Genomic Data: Single-Cell Insights into Salivary Gland Biology and Disease.Biology · 2026Review
- Unveiling critical signaling pathways in the murine salivary gland and the role of midkine.iScience · 2026Article
- Article
- Promoting Polarization and Differentiation of Primary Human Salivary Gland Stem/Progenitor Cells in Protease-Degradable Hydrogels via ROCK Inhibition.ACS applied materials & interfaces · 2025Article
- Salivary gland organoid transplantation as a therapeutic option for radiation-induced xerostomia.Stem cell research & therapy · 2024Article
- Transcription factor FoxO1 regulates myoepithelial cell diversity and growth.Scientific reports · 2024Article
- Isolation and Functional Analysis of Myoepithelial Cells from Adult Mouse Submandibular Glands.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Article
- Salivary Gland Bioengineering.Bioengineering (Basel, Switzerland) · 2023Review
- CSF1R-dependent macrophages in the salivary gland are essential for epithelial regeneration after radiation-induced injury.Science immunology · 2023Article
- Evaluating the transcriptional landscape and cell-cell communication networks in chronically irradiated parotid glands.iScience · 2023Article
- Bulk RNA-seq and scRNA-seq analysis reveal an activation of immune response and compromise of secretory function in major salivary glands of obese mice.Computational and structural biotechnology journal · 2023Article
- Retinoic acid and FGF10 promote the differentiation of pluripotent stem cells into salivary gland placodes.Stem cell research & therapy · 2022Article
- Salivary gland function, development, and regeneration.Physiological reviews · 2022Review
- Optimizing Soluble Cues for Salivary Gland Tissue Mimetics Using a Design of Experiments (DoE) Approach.Cells · 2022Article
- The submandibular and sublingual glands maintain oral microbial homeostasis through multiple antimicrobial proteins.Frontiers in cellular and infection microbiology · 2022Article
- Review
- Organoid Models for Salivary Gland Biology and Regenerative Medicine.Stem cells international · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Mammalian salivary glands synthesize and secrete saliva via a vast interconnected network of epithelial tubes attached to secretory end units. The extensive morphogenesis required to establish this organ is dependent on interactions between multiple cell types (epithelial, mesenchymal, endothelial, and neuronal) and the engagement of a wide range of signaling pathways. Here we describe critical regulators of salivary gland development and discuss how mutations in these impact human organogenesis. In particular, we explore the genetic contribution of growth factor pathways, nerve-derived factors and extracellular matrix molecules to salivary gland formation in mice and humans.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.