ArticleJournal of cardiovascular electrophysiology2015
The Evolution of Tissue Stiffness at Radiofrequency Ablation Sites During Lesion Formation and in the Peri-Ablation Period.
Article in Journal of cardiovascular electrophysiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 30 citations in OpenAlex.
- The role of pulsed electric field therapy in non-small cell lung cancer: a narrative review of a novel minimally invasive intervention.Journal of thoracic disease · 2026Review
- Image-Based Monitoring of Thermal Ablation.Bioengineering (Basel, Switzerland) · 2025Review
- Treatment efficacy prediction of focused ultrasound therapies using multi-parametric magnetic resonance imaging.Cancer prevention, detection, and intervention : Third MICCAI Workshop, CaPTion 2024, Held in Conjunction with MICCAI 2024, Marrakesh, Morocco, October 6, 2024, Proceedings. CaPTion (Workshop) (3rd : 2024 : Marrakech, Morocco) · 2025Article
- Therapeutic ultrasound transducer technology and monitoring techniques: a review with clinical examples.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2024Review
- Magnetic resonance shear wave elastography using transient acoustic radiation force excitations and sinusoidal displacement encoding.Physics in medicine and biology · 2021Article
- Catheter Ablation Lesion Visualization With Intracardiac Strain Imaging in Canines and Humans.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2020Article
- Assessment of Diastolic Function Using Ultrasound Elastography.Ultrasound in medicine & biology · 2018Article
- Spectroscopic photoacoustic imaging of radiofrequency ablation in the left atrium.Biomedical optics express · 2018Article
- Early and Delayed Alteration of Atrial Electrograms Around Single Radiofrequency Ablation Lesion.Frontiers in cardiovascular medicine · 2018Article
- Increased matrix stiffness promotes tumor progression of residual hepatocellular carcinoma after insufficient heat treatment.Cancer science · 2017Article
- Pulmonary Vein Isolation Lesion Set Assessment During Radiofrequency Catheter Ablation for Atrial Fibrillation.The Journal of innovations in cardiac rhythm management · 2017Review
- Quantifying Myocardial Contractility Changes Using Ultrasound-Based Shear Wave Elastography.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2017Article
- A Comparison of Acoustic Radiation Force-Derived Indices of Cardiac Function in the Langendorff Perfused Rabbit Heart.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2016Article
- Improving Displacement Signal-to-Noise Ratio for Low-Signal Radiation Force Elasticity Imaging Using Bayesian Techniques.Ultrasound in medicine & biology · 2016Article
- Robust Tracking of Small Displacements With a Bayesian Estimator.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2016Article
- Article
- Making better scar: Emerging approaches for modifying mechanical and electrical properties following infarction and ablation.Progress in biophysics and molecular biology · 2016Review
- Personalized biomechanical insights in atrial fibrillation: opportunities & challenges.Expert review of cardiovascular therapyReview
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
introductionElastography imaging can provide radiofrequency ablation (RFA) lesion assessment due to tissue stiffening at the ablation site. An important aspect of assessment is the spatial and temporal stability of the region of stiffness increase in the peri-ablation period. The aim of this study was to use 2 ultrasound-based elastography techniques, shear wave elasticity imaging (SWEI) and acoustic radiation force impulse (ARFI) imaging, to monitor the evolution of tissue stiffness at ablation sites in the 30 minutes following lesion creation. METHODS AND
resultsIn 6 canine subjects, SWEI measurements and 2-D ARFI images were acquired at 6 ventricular endocardial RFA sites before, during, and for 30 minutes postablation. An immediate increase in tissue stiffness was detected during RFA, and the area of the postablation region of stiffness increase (RoSI) as well as the relative stiffness at the RoSI center was stable approximately 2 minutes after ablation. Of note is the observation that relative stiffness in the region adjacent to the RoSI increased slightly during the first 15 minutes, consistent with local fluid displacement or edema. The magnitude of this increase, ∼0.5-fold from baseline, was significantly less than the magnitude of the stiffness increase directly inside the RoSI, which was greater than 3-fold from baseline.
conclusionsUltrasound-based SWEI and ARFI imaging detected an immediate increase in tissue stiffness during RFA, and the stability and magnitude of the stiffness change suggest that consistent elasticity-based lesion assessment is possible 2 minutes after and for at least 30 minutes following ablation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.