ReviewThe New England journal of medicine2015
Clinical practice. Acute appendicitis--appendectomy or the "antibiotics first" strategy.
Review in The New England journal of medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 86 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
86 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- The SIFIPAC/WSES/SICG/SIMEU guidelines for diagnosis and treatment of acute appendicitis in the elderly (2019 edition).World journal of emergency surgery : WJES · 2020Guideline
- Effect of Delay to Operation on Outcomes in Patients with Acute Appendicitis: a Systematic Review and Meta-analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2019Pooled it
- Antibiotics Versus Appendicectomy for the Treatment of Uncomplicated Acute Appendicitis: An Updated Meta-Analysis of Randomised Controlled Trials.World journal of surgery · 2016Pooled it
- Evidence for an Antibiotics-First Strategy for Uncomplicated Appendicitis in Adults: A Systematic Review and Gap Analysis.Journal of the American College of Surgeons · 2016Pooled it
- Endoscopic retrograde appendicitis therapy versus laparoscopic appendectomy versus open appendectomy for acute appendicitis: a pilot study.BMC gastroenterology · 2022Trial
- Acute Appendicitis: Still a Surgical Disease? Results from a Propensity Score-Based Outcome Analysis of Conservative Versus Surgical Management from a Prospective Database.World journal of surgery · 2017Trial
- Antibiotics-First Versus Surgery for Appendicitis: A US Pilot Randomized Controlled Trial Allowing Outpatient Antibiotic Management.Annals of emergency medicine · 2017Trial
- Article
- Impact of the COVID-19 pandemic on the pattern of acute appendicitis, a single-center study.Frontiers in surgery · 2026Article
- Oral antibiotic therapy without hospitalization in uncomplicated acute appendicitis: long-term results from a retrospective cohort study.International journal of colorectal disease · 2025Article
- Impact of peritoneal lavage on intra-abdominal abscess after laparoscopic appendectomy for perforated appendicitis: a propensity score matching analysis.BMC gastroenterology · 2025Article
- Nonoperative treatment of neonatal appendicitis.BMC pediatrics · 2025Article
- Article
- Review
- Clinical outcomes and optimal indications for nonoperative management of acute appendicitis in adult patients: a comprehensive literature review.Annals of coloproctology · 2025Review
- Acute appendicitis and its treatment: a historical overview.International journal of colorectal disease · 2025Article
- Diagnostic and therapeutic value of appendoscope-assisted endoscopic retrograde appendicitis therapy.Endoscopy international open · 2025Article
- Robot-assisted laparoscopic treatment of appendicovesical fistula in a child: a case report and literature review.Frontiers in pediatrics · 2025Article
- Indication of conservative treatment by antibiotics for uncomplicated and complicated acute appendicitis.World journal of gastrointestinal surgery · 2024Article
- Interhospital variation in the non-operative management of uncomplicated appendicitis in adults.Surgery open science · 2024Article
26 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
25970051What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.