ArticleBioPsychoSocial medicine2015
Inpatient and outpatient costs in patients with coronary artery disease and mental disorders: a systematic review.
Article in BioPsychoSocial medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 4 of them syntheses that pooled it.
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Who cites it
38 citing papers in PubMed, 4 syntheses or guidelines pooled it, 75 citations in OpenAlex.
- Global comparison of the economic costs of coronary heart disease: a systematic review and meta-analysis.BMJ open · 2025Pooled it
- Psychological interventions for depression and anxiety in patients with coronary heart disease, heart failure or atrial fibrillation.The Cochrane database of systematic reviews · 2024Pooled it
- Psychological and pharmacological interventions for depression in patients with coronary artery disease.The Cochrane database of systematic reviews · 2021Pooled it
- Pooled it
- Trial
- Cardiovascular Health in Anxiety or Mood Problems Study (CHAMPS): study protocol for a randomized controlled trial.Trials · 2016Trial
- Metacognitive Therapy in Cardiac Rehabilitation: Staff Barriers and Enablers to Training in an Evidence-Based Psychological Treatment for Anxiety and Depression.Journal of the American Heart Association · 2026Article
- Implementing group metacognitive therapy to improve mental health in NHS cardiac rehabilitation: the PATHWAY beacons study of adoption, adherence and data capture.Frontiers in health services · 2026Article
- Impact of Mental Health Disorders in Patients with Myocardial Infarction with Non-obstructive Coronary Arteries: A Propensity Score-Matched Nationwide Analysis.Journal of general internal medicine · 2025Article
- Enhancing long-term adherence in elderly stroke rehabilitation through a digital health approach based on multimodal feedback and personalized intervention.Scientific reports · 2025Article
- The combined effects of depression or anxiety with high-sensitivity C-reactive protein in predicting the prognosis of coronary heart disease patients.BMC psychiatry · 2024Article
- Impact of Mental Health Treatment on Outcomes in Patients With Heart Failure and Ischemic Heart Disease.Journal of the American Heart Association · 2024Article
- Protocol for an implementation study of group metacognitive therapy for anxiety and depression in NHS cardiac rehabilitation services in England (PATHWAY-Beacons).Frontiers in health services · 2024Article
- The mediating role of sleep disturbance in the relationship between depression and cardiovascular disease.Frontiers in psychiatry · 2024Article
- Comorbidity between major depressive disorder and physical diseases: a comprehensive review of epidemiology, mechanisms and management.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2023Article
- Levels of depressive symptoms in cardiac patients attending cardiac rehabilitation with a history of depression: pre Covid-19 and Covid-19 period comparison.BMC cardiovascular disorders · 2022Article
- Transdiagnostic Cognitive-Behavioral Therapy for Depression and Anxiety Disorders in Cardiovascular Disease Patients: Results From the CHAMPS Pilot-Feasibility Trial.Frontiers in psychiatry · 2022Article
- Comorbidity of depression and anxiety leads to a poor prognosis following angina pectoris patients: a prospective study.BMC psychiatry · 2021Article
- Lessons learned from an attempted randomized-controlled feasibility trial on "WIDeCAD" - An internet-based depression treatment for people living with coronary artery disease (CAD).Internet interventions · 2021Article
- Identification of psychiatric patients with high mortality and low medical utilization: a population-based propensity score-matched analysis.BMC health services research · 2020Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo systematically review in- and outpatient costs in patients with coronary artery disease (CAD) and comorbid mental disorders.
methodsA comprehensive database search was conducted for studies investigating persons with CAD and comorbid mental disorders (Medline, EMBASE, PsycINFO, Psyndex, EconLit, IBSS). All studies were included which allowed a comparison of in- and outpatient health care costs (assessed either monetarily or in terms of health care utilization) of CAD patients with comorbid mental disorders (mood, anxiety, alcohol, eating, somatoform and personality disorders) and those without. Random effects meta-analyses were conducted and results reported using forest plots.
resultsThe literature search resulted in 7,275 potentially relevant studies, of which 52 met inclusion criteria. Hospital readmission rates were increased in CAD patients with any mental disorder (pooled standardized mean difference (SMD) = 0.34 [0.17;0.51]). Results for depression, anxiety and posttraumatic stress disorder pointed in the same direction with heterogeneous SMDs on a primary study level ranging from -0.44 to 1.26. Length of hospital stay was not increased in anxiety and any mental disorder, while studies on depression reported heterogeneous SMDs ranging from -0.08 to 0.82. Most studies reported increased overall and outpatient costs for patients with comorbid mental disorders. Results for invasive procedures were non-significant respectively inconclusive.
conclusionsComorbid mental disorders in CAD patients are associated with an increased healthcare utilization in terms of higher hospital readmission rates and increased overall and outpatient health care costs. From a health care point of view, it is requisite to improve the diagnosis and treatment of comorbid mental disorders in patients with CAD to minimize incremental costs.
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