Evidence map›Paper›PMID 25969671›Full record

ArticleThrombosis journal2015

Autoinflammatory diseases: a possible cause of thrombosis?

Micaela La Regina, Francesco Orlandini, Raffaele Manna

Abstract read
In one paragraph

Article in Thrombosis journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. VEXAS Syndrome: A Novelty in MDS Landscape.Diagnostics (Basel, Switzerland) · 2022
    Review
  4. Article
  5. Autoinflammatory Diseases and Physical Therapy.Mediterranean journal of rheumatology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Micaela La ReginaDepartment of Internal Medicine, Ligurian East Hospital, La Spezia, Italy.
Francesco OrlandiniDepartment of Internal Medicine, Ligurian East Hospital, La Spezia, Italy.
Raffaele MannaCentre of Periodic Fevers - Catholic University of Rome, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoinflammatory diseases are a group of disorders due to acquired or hereditary disfunction of innate immune system and characterized by systemic or localized manifestations. The prototype is Familial Mediterranean Fever, a monogenic hereditary disorder, whose causing gene (MeFV gene) was identified in 1997 and opened the way to a new fascinanting chapter of rheumatology. A growing body of monogenic and poligenic autoinflammatory disorders has been described since then. Arterial and venous thrombosis is a common medical problem, with significant morbidity and mortality. Strong evidences from basic research and clinical epidemiological studies support the theory that inflammation and thrombosis can be associated. Because of their recurrent/chronic inflammatory nature, autoinflammatory diseases are a putative cause of thrombotic manifestations. In the present work, we reviewed the available evidences about monogenic autoinflammatory disorders, complicated by thrombotic manifestations.

Indexed as

Arterial thrombosisAutoinflammatory diseasesCriopyrinopathiesFamilial mediterranean feverMyocardial infarctionPeriodic feversPyrinopathiesStrokeVenous thromboembolismVenous thrombosis

Identifiers

PMID25969671
PMCPMC4428094

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.