ArticleObesity facts2015
Long-Term Normal Renal Function after Drastic Weight Reduction in Patients with Obesity-Related Glomerulopathy.
Article in Obesity facts, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 28 citations in OpenAlex.
- Untargeted Urinary Proteomics Uncovers Nephroprotective and Systemic Adaptations after Obesity Surgery-Induced Weight Loss.Journal of proteome research · 2026Article
- Effect of Roux-En-Y Gastric Bypass on Albuminuria in Morbidly Obese Patients with Type-2 Diabetes Mellitus: A Prospective Non-Randomized Controlled Study with 15-Month Follow-Up.International journal of general medicine · 2026Article
- Novel Therapeutic Strategies for Obesity-Related Glomerulopathy.Current hypertension reports · 2025Review
- Obesity-related glomerulopathy: How it happens and future perspectives.Diabetic medicine : a journal of the British Diabetic Association · 2025Review
- The Impact of Early-Stage Chronic Kidney Disease on Weight Loss Outcomes After Gastric Bypass.Obesity surgery · 2023Article
- Targeting Renal Proximal Tubule Cells in Obesity-Related Glomerulopathy.Pharmaceuticals (Basel, Switzerland) · 2023Review
- Obesity-related glomerulopathy: Current approaches and future perspectives.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022Review
- Obesity and CKD in Sub-Saharan Africa: A Narrative Review.Kidney medicine · 2022Review
- Renal Function and Bariatric Surgery: an Ongoing Debate.Obesity surgery · 2022Article
- Renoprotective role of bariatric surgery in patients with established chronic kidney disease.Clinical kidney journal · 2021Article
- Bariatric Surgery Is Protective Against Renal Function Decline in Severely Obese Patients in the Long-Term.Obesity surgery · 2021Article
- Obesity-Related Glomerulopathy: From Mechanism to Therapeutic Target.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Review
- Range of adiposity and cardiorenal syndrome.World journal of diabetes · 2020Review
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- Article
- Albuminuria in Patients with Morbid Obesity and the Effect of Weight Loss Following Bariatric Surgery.Obesity surgery · 2019Article
- Effects of sleeve gastrectomy on lipid and energy metabolism in ZDF rats via PI3K/AKT pathway.American journal of translational research · 2018Article
- Obesity-related glomerulopathy: pathogenesis, pathologic, clinical characteristics and treatment.Frontiers of medicine · 2017Review
- Consequences of morbid obesity on the kidney. Where are we going?Clinical kidney journal · 2016Article
- Obesity-related glomerulopathy: clinical and pathologic characteristics and pathogenesis.Nature reviews. Nephrology · 2016Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsNo long-term studies of renal function evolution in morbidly obese (MO) patients after weight loss are available. The aim of our work was to ascertain the long-term influence of drastic weight reduction on renal function in MO patients with obesity-related glomerular lesions.
methods92 MO patients with normal renal function and biopsy evidence of mild obesity-related glomerulopathy underwent bariatric surgery (BS) and subsequent drastic weight loss. A long-term prospective follow-up (mean duration: 76 ± 42 months) was carried out. Basal renal biopsies and basal and long-term metabolic and renal function studies were performed in all cases. Linear mixed models were applied.
resultsBlood pressure dropped early after BS and remained stable thereafter. Creatinine clearance and BMI fell in the first 2 years, rose slightly after 5 years and then remained stable. Serum creatinine and albuminuria decreased throughout the follow-up period. Renal function and albuminuria evolution showed non-significant differences in relation to the number of glomerular lesions.
conclusionsDrastic weight loss in BS-treated MO patients with pre-surgical normal renal function and mild obesity-related glomerular lesions is associated with short- and long-term maintenance of normal renal function and improvement in both arterial hypertension and albuminuria.
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