Evidence map›Paper›PMID 25968492›Full record

ArticleInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2015

Assessment of the impact of rapid syphilis tests on syphilis screening and treatment of pregnant women in Zambia.

Rachael E Bonawitz, Julie Duncan, Emily Hammond, Leoda Hamomba, Jane Nambule, Kennedy Sambambi, Victor Musonda, Alana Calise, Anna Knapp, Jonas Mwale and 3 more

Abstract read
In one paragraph

Article in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  18. [Health-worker barriers to syphilis screening in pregnant women in Bolivia's Los Andes network].Revista panamericana de salud publica = Pan American journal of public health · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Rachael E BonawitzCenter for Global Health and Development, Boston University, Boston, MA, USA; Department of Pediatrics, Boston Medical Center, Boston, MA, USA. Electronic address: rachael.bonawitz@bmc.org.
Julie DuncanZambia Center for Applied Health Research and Development, Lusaka, Zambia.
Emily HammondCenter for Global Health and Development, Boston University, Boston, MA, USA.
Leoda HamombaZambia Center for Applied Health Research and Development, Lusaka, Zambia.
Jane NambuleZambia Center for Applied Health Research and Development, Lusaka, Zambia.
Kennedy SambambiZambia Center for Applied Health Research and Development, Lusaka, Zambia.
Victor MusondaZambia Center for Applied Health Research and Development, Lusaka, Zambia.
Alana CaliseGlobal Health, Boston University School of Public Health, Boston, MA, USA.
Anna KnappCenter for Global Health and Development, Boston University, Boston, MA, USA.
Jonas MwaleUS Centers for Disease Control and Prevention, Lusaka, Zambia.
James McCauleyUS Centers for Disease Control and Prevention, Lusaka, Zambia.
Donald TheaCenter for Global Health and Development, Boston University, Boston, MA, USA; Global Health, Boston University School of Public Health, Boston, MA, USA.
Julie M HerlihyCenter for Global Health and Development, Boston University, Boston, MA, USA; Department of Pediatrics, Boston Medical Center, Boston, MA, USA; Global Health, Boston University School of Public Health, Boston, MA, USA.

Funding

A PROPOSAL TO SUPPORT DISTRICT-LEVEL IMPLEMENTATION OF THE ZAMBIA MINISTRY OF HEAU2GPS001418 · PS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI THEA, DONALD M · 2009 to 2014
$23.8M
NCHHSTP CDC HHS U2G PS001418
6 · The paper itself

Abstract

objectiveTo evaluate the impact of rapid syphilis tests (RSTs) on syphilis testing and treatment in pregnant women in Kalomo District, Zambia.

methodsIn March 2012, health workers at all 35 health facilities in Kalomo Distract were trained in RST use and penicillin treatment. In March 2013, data were retrospectively abstracted from 18 randomly selected health facilities and stratified into three time intervals: baseline (6months prior to RST introduction), midline (0-6 months after RST introduction), and endline (7-12 months after RST introduction).

resultsData collected on 4154 pregnant women showed a syphilis-reactive seroprevalence of 2.7%. The proportion of women screened improved from baseline (140/1365, 10.6%) to midline (976/1446, 67.5%), finally decreasing at endline (752/1337, 56.3%) (P<0.001). There was no significant difference in the proportion of syphilis-seroreactive pregnant women who received 1 dose of penicillin before (1/2, 50%) or after (5/48, 10.4%; P=0.199) RST introduction with low treatment rates throughout.

conclusionWith RST scale-up in Zambia and other resource-limited settings, same-day test and treatment with penicillin should be prioritized to achieve the goal of eliminating congenital syphilis.

Indexed as

AdultFemaleHealth Impact AssessmentHumansMass ScreeningPenicillinsPregnancyPregnancy Complications, InfectiousPrenatal DiagnosisRetrospective StudiesSyphilisTime FactorsZambiaPenicillinsAntenatal careCongenital syphilisPenicillinRapid syphilis tests

Identifiers

PMID25968492
PMCPMC8991823

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.