ArticleThe journal of headache and pain2015
Resting state brain activity in patients with migraine: a magnetoencephalography study.
Article in The journal of headache and pain, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00600717 (Localizing Functional Brain Cortices and Epileptogenic Zones With High Frequency Brain Signals), which is not on this map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Localizing Functional Brain Cortices and Epileptogenic Zones With High Frequency Brain Signals
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Magnetoencephalography studies in migraine and headache disorders: A systematic review.Headache · 2025Pooled it
- Resting-state electroencephalography and magnetoencephalography in migraine-a systematic review and meta-analysis.The journal of headache and pain · 2024Pooled it
- An Overview of Prosopagnosia as a Symptom of Migraine: A Literature Review.Current pain and headache reports · 2025Review
- Altered neuromagnetic activity under visual stimuli in migraine: a multi-frequency magnetoencephalography study.Frontiers in neurology · 2025Article
- Electroencephalographic signatures of migraine in small prospective and large retrospective cohorts.Scientific reports · 2024Article
- Diagnostic biomarker discovery from brain EEG data using LSTM, reservoir-SNN, and NeuCube methods in a pilot study comparing epilepsy and migraine.Scientific reports · 2024Article
- Specifically formulated ketogenic, low carbohydrate, and carnivore diets can prevent migraine: a perspective.Frontiers in nutrition · 2024Article
- Excitation-Inhibition Imbalance in Migraine: From Neurotransmitters to Brain Oscillations.International journal of molecular sciences · 2023Review
- Article
- Resting State Electrophysiological Cortical Activity: A Brain Signature Candidate for Patients with Migraine.Current pain and headache reports · 2022Review
- Altered Neuromagnetic Activity in Persistent Postural-Perceptual Dizziness: A Multifrequency Magnetoencephalography Study.Frontiers in human neuroscience · 2022Article
- Individual pain sensitivity is associated with resting-state cortical activities in healthy individuals but not in patients with migraine: a magnetoencephalography study.The journal of headache and pain · 2020Article
- Genetic Screening of Plasticity Regulating Nogo-Type Signaling Genes in Migraine.Brain sciences · 2019Article
- Does the migraine attack start in the cortex and is the cortex critical in the migraine process?Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2019Review
- Abnormal functional connectivity under somatosensory stimulation in migraine: a multi-frequency magnetoencephalography study.The journal of headache and pain · 2019Article
- Functional connectivity and cognitive impairment in migraine with and without aura.The journal of headache and pain · 2017Article
- Quantitative neuromagnetic signatures of aberrant cortical excitability in pediatric chronic migraine.The journal of headache and pain · 2016Article
- Multi-frequency analysis of brain connectivity networks in migraineurs: a magnetoencephalography study.The journal of headache and pain · 2016Article
- Cortical mechanisms in migraine.Molecular painArticle
- Voxel-based quantitative susceptibility mapping revealed increased cerebral iron over the whole brain in chronic migraine.Molecular painArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecent advances in migraine research have shown that the cerebral cortex serves a primary role in the pathogenesis of migraine. Since aberrant brain activity in migraine can be noninvasively detected with magnetoencephalography (MEG), The object of this study was to investigate the resting state cortical activity differences between migraineurs and controls and its related clinical characteristics.
methodsTwenty-two subjects with an acute migraine and twenty-two age- and gender-matched controls were studied using MEG. MEG recordings were recorded 120 seconds during the headache attack. Analyze MEG signals from low (1-4 Hz) to high (200-1000 Hz)-frequency ranges.
resultsIn comparison with the controls, brain activity in migraine subjects was significantly different from that of the controls both in two frequency ranges (55-90 Hz, p < 0.001) and (90-200 Hz, p < 0.004). But the power value showed no significantly differences between control and migraines in all frequency ranges (p > 0.05). All the clinical characteristics had no significant correlation with aberrant brain activity.
conclusionsThe results demonstrated that migraine subjects in resting state had significantly aberrant ictal brain activity that can be measured with neuromagnetic imaging techniques. The findings may facilitate the development of new therapeutic strategies in migraine treatment via alterations in cortical excitability with TMS and other medications in the future.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.