Evidence map›Paper›PMID 25967985›Full record

ArticleBMJ open2015

Quantifying the utility of taking pills for preventing adverse health outcomes: a cross-sectional survey.

Robert Hutchins, Michael P Pignone, Stacey L Sheridan, Anthony J Viera

Abstract read
In one paragraph

Article in BMJ open, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Robert HutchinsHealth Care and Prevention MD-MPH Program, University of North Carolina at Chapel Hill School of Medicine and Gillings School of Global Public Health, Chapel Hill, North Carolina, USA.
Michael P PignoneDepartment of Medicine, Division of General Internal Medicine and Clinical Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Stacey L SheridanHealth Care and Prevention MD-MPH Program, University of North Carolina at Chapel Hill School of Medicine and Gillings School of Global Public Health, Chapel Hill, North Carolina, USA Department of Medicine, Division of General Internal Medicine and Clinical Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Anthony J VieraHealth Care and Prevention MD-MPH Program, University of North Carolina at Chapel Hill School of Medicine and Gillings School of Global Public Health, Chapel Hill, North Carolina, USA Department of Family Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe utility value attributed to taking pills for prevention can have a major effect on the cost-effectiveness of interventions, but few published studies have systematically quantified this value. We sought to quantify the utility value of taking pills used for prevention of cardiovascular disease (CVD).

designCross-sectional survey.

settingCentral North Carolina.

participants708 healthcare employees aged 18 years and older. PRIMARY AND SECONDARY OUTCOMES: Utility values for taking 1 pill/day, assessed using time trade-off, modified standard gamble and willingness-to-pay methods.

resultsMean age of respondents was 43 years (19-74). The majority of the respondents were female (83%) and Caucasian (80%). Most (80%) took at least 2 pills/day. Mean utility values for taking 1 pill/day using the time trade-off method were: 0.9972 (95% CI 0.9962 to 0.9980). Values derived from the standard gamble and willingness-to-pay methods were 0.9967 (0.9954 to 0.9979) and 0.9989 (95% CI 0.9986 to 0.9991), respectively. Utility values varied little across characteristics such as age, sex, race, education level or number of pills taken per day.

conclusionsThe utility value of taking pills daily in order to prevent an adverse CVD health outcome is approximately 0.997.

Indexed as

Attitude to HealthPatient ComplianceQuality of LifeAdultAgedCardiovascular AgentsCardiovascular DiseasesCross-Sectional StudiesDrug Administration ScheduleFemaleHumansMaleMiddle AgedNorth CarolinaPharmaceutical PreparationsPreventive MedicineCardiovascular AgentsPharmaceutical Preparationscost-effectivenessmedical decision makingutility analysis

Identifiers

PMID25967985
PMCPMC4431138

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.