Evidence map›Paper›PMID 25967582›Full record

ArticleAnnals of behavioral medicine : a publication of the Society of Behavioral Medicine2015

Heightened Temporal Summation of Pain in Patients with Functional Gastrointestinal Disorders and History of Trauma.

Amanda L Sherman, Matthew C Morris, Stephen Bruehl, Travis D Westbrook, Lynn S Walker

2 registry-linked trialsOpen access · bronzeAbstract read
In one paragraph

Article in Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
6.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04275297 nacompletednot on this mapstarted 2020, after this paper: background citation

Optimizing Psychosocial Treatment of Interstitial Cystitis/Bladder Pain Syndrome

TypeinterventionalSponsorVanderbilt University Medical CenterRan2020 to 2023Enrolled78ConditionsChronic Interstitial Cystitis, Bladder Pain Syndrome, Cystitis, Interstitial, Painful Bladder SyndromeArmsPsychosocial Treatment, Attention Control
NCT06299683 narecruitingnot on this mapstarted 2024, after this paper: background citation

Mechanistic-Based Treatment of Interstitial Cystitis/Bladder Pain Syndrome

TypeinterventionalSponsorVanderbilt University Medical CenterRan2024 to 2028Enrolled220ConditionsChronic Interstitial Cystitis, Bladder Pain Syndrome, Painful Bladder Syndrome, Cystitis, InterstitialArmsPsychosocial Treatment, Pelvic Floor Physical Therapy
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 50 citations in OpenAlex.

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  19. Fibromyalgia and its New Lessons for Neuropsychiatry.Medical science monitor basic research · 2019
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Amanda L ShermanDepartment of Psychology and Human Development, Vanderbilt University, Nashville, TN, USA.
Matthew C MorrisDepartment of Family and Community Medicine, Meharry Medical College, Nashville, TN, USA.
Stephen BruehlDepartment of Anesthesiology, Vanderbilt University School of Medicine, Nashville, TN, USA.
Travis D WestbrookDepartment of Psychology, The Ohio State University, Columbus, OH, USA.
Lynn S WalkerDepartment of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN, USA. lynn.walker@vanderbilt.edu.
Vanderbilt University · USMeharry Medical College · USThe Ohio State University · US

Funding

VANDERBILT UNIVERSITY CTSA FOR PEDIATRIC RESEARCHUL1RR024975 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$45.7M
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
THREE-TIERED PREVENTION MODEL TO BETTER SERVE ALL STUDENP30HD015052 · NICHD · VANDERBILT UNIVERSITY · PI DYKENS, ELISABETH MAY · 1985 to 2014
$18.6M
Meharry RCMI Program in Women's Health ResearchG12MD007586 · NIMHD · MEHARRY MEDICAL COLLEGE · PI HILDRETH, JAMES E · 2012 to 2016
$7.8M
ILLNESS BEHAVIOR AND SOMATIZATION IN CHILDRENR01HD023264 · NICHD · VANDERBILT UNIVERSITY · PI WALKER, LYNN D. · 1987 to 2011
$3.9M
Predictors of Opioid Analgesic Responses and Common Endogenous Opioid MechanismsR01DA031726 · NIDA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BRUEHL, STEPHEN, BURNS, JOHN W. · 2011 to 2015
$2.7M
Models of Risk for PTSDK01MH101403 · NIMH · MEHARRY MEDICAL COLLEGE · PI MORRIS, MATTHEW C. · 2013 to 2017
$872k
NCRR NIH HHS 1 UL1 RR024975NCRR NIH HHS UL1 RR024975NICHD NIH HHS P30 HD015052NICHD NIH HHS P30 HD15052NICHD NIH HHS R01 HD023264NICHD NIH HHS R01 HD23264NIDA NIH HHS R01 DA031726NIDDK NIH HHS DK058404NIDDK NIH HHS P30 DK058404NIMHD NIH HHS G12 MD007586NIMH NIH HHS K01 MH101403
6 · The paper itself

Abstract

backgroundIndividuals with functional gastrointestinal disorders (FGIDs) report experiencing trauma more often than healthy controls, but little is known regarding psychophysical correlates. PURPOSE: The purpose of this study was to test the hypothesis that adolescents and young adults with FGIDs since childhood and a trauma history (n = 38) would exhibit heightened temporal summation to thermal pain stimuli, an index of central sensitization, and greater clinical symptoms compared to patients with FGIDs and no trauma history (n = 95) and healthy controls (n = 135).

methodsParticipants completed self-report measures, an experimental pain protocol, and psychiatric diagnostic interview as part of a larger longitudinal study.

resultsFGID + Trauma patients exhibited greater temporal summation than FGID + No Trauma patients and healthy controls. Additionally, FGID + Trauma patients exhibited greater gastrointestinal and non-gastrointestinal symptom severity, number of chronic pain sites, and disability.

conclusionsAssessing for trauma history in patients with FGIDs could identify a subset at risk for greater central sensitization and pain-related symptoms.

Indexed as

AdolescentAdult Survivors of Child Adverse EventsFemaleGastrointestinal DiseasesHumansLongitudinal StudiesMalePainPain PerceptionSelf ReportSurveys and QuestionnairesYoung AdultCentral sensitizationChronic painFunctional abdominal painTemporal summationTrauma

Identifiers

PMID25967582
PMCPMC4636446
OpenAlexW256804408

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.