ArticleExperimental biology and medicine (Maywood, N.J.)2016
The effects of energy intake of four different feeding patterns in rats.
Article in Experimental biology and medicine (Maywood, N.J.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Combined Lutein and Exercise Intervention Alleviates Brain Alteration Induced by a High-Fat Diet in Obese Rats.Food science & nutrition · 2026Article
- Antioxidant Activity of Crocodile Oil (Foods (Basel, Switzerland) · 2023Article
- Evaluation of the Anti-Obesity Effect of Zeaxanthin and Exercise in HFD-Induced Obese Rats.Nutrients · 2022Article
- Differential microRNAs expression profiles in liver from three different lifestyle modification mice models.BMC genomics · 2021Article
- Dietary Intervention, When Not Associated With Exercise, Upregulates Irisin/FNDC5 While Reducing Visceral Adiposity Markers in Obese Rats.Frontiers in physiology · 2021Article
- Modeling energy intake and body weight effects of a long-acting amylin analogue.Journal of pharmacokinetics and pharmacodynamics · 2018Article
- In utero exposure to germinated brown rice and its oryzanol-rich extract attenuated high fat diet-induced insulin resistance in F1 generation of rats.BMC complementary and alternative medicine · 2017Article
- Evaluation of candidate reference genes for RT-qPCR studies in three metabolism related tissues of mice after caloric restriction.Scientific reports · 2016Article
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Authors and funding
7 authors.
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Abstract
Energy intake can affect the metabolism. But it is not very clear that how and to what degree the metabolism can be changed by energy intake quantity and change. Here we applied four feeding patterns in male Sprague-Dawley rats--normal ad libitum diet (NFal), high-fat diet (HFal), caloric restriction (CR) after HFal (HFal-NFcr), and refeeding from CR to ad libitum (HFal-NFcr-NFal). Food intake and body weight, along with fat mass, insulin sensitivity, fasting plasma insulin, and glucose level were used to calculate the energy efficiency and compared the quantitative effects of energy intake. Energy intake changed little in NFal or HFal group; while it changed greatly and suddenly in HFal-NFcr or HFal-NFcr-NFal group. All the parameters we detected were different between these four feeding patterns. Excess of energy intake from high-fat diet induced adverse outcomes with low energy efficiency. CR reversed the impairment of high-fat diet with very high energy efficiency in a short period. However, dramatic response with high energy efficiency induced by recovery to feeding ad libitum after CR, which was possible harmful to health. In conclusion, energy intake quantity and change are key determinants of metabolism. Different energy intake quantity and change affect body weight, white adipose tissue weight, insulin sensitivity, etc. at different degrees and speeds because of different energy efficiency.
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