ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2015
The search for endocarditis in patients with candidemia: a systematic recommendation for echocardiography? A prospective cohort.
Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Brazilian guidelines for the diagnosis and treatment of candidemia and invasive candidiasis in adults and children.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious DiseasesGuideline
- Association of antifungal treatment duration with 90-day mortality in critically ill adults with candidemia: a multicenter target trial emulation in France.EClinicalMedicine · 2026Article
- Diagnostic, cardiac imaging, and management considerations in fungal infective endocarditis: a contemporary narrative review.Cardiovascular diagnosis and therapy · 2026Review
- Invasive Candidiasis in Critically Ill Patients: Fundamental Concepts and Future Directions.Chest · 2026Review
- Fungal endocarditis. A retrospective analysis from a high-volume surgical centre and review of the literature.BMC infectious diseases · 2025Review
- Candida.JHLT open · 2025Article
- A Review of Current Insights in Fungal Endocarditis.Journal of clinical medicine · 2025Review
- Epidemiology, Risk Factors and Clinical Outcome of Candidaemia:Sultan Qaboos University medical journal · 2025Observational
- Candida Infectious Endocarditis and Implantable Cardiac Device Infections.Mycopathologia · 2023Review
- Candida endocarditis: Update on management considerations.World journal of cardiology · 2023Review
- Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management.Clinical microbiology reviews · 2023Review
- Determining the usefulness of systematicBMJ open · 2023Article
- Ophthalmologic Examination and Echocardiography Should be the Essential Components of Candidemia Bundle.Infectious diseases & clinical microbiology · 2023Article
- Association between Following the ESCMID Guidelines for the Management of Candidemia and Mortality: A Retrospective Cohort Study.Journal of fungi (Basel, Switzerland) · 2022Article
- The Utility of EQUAL Candida Score in Predicting Mortality in Patients with Candidemia.Journal of fungi (Basel, Switzerland) · 2022Article
- Candida Endocarditis in Patients with Candidemia: A Single-Center Experience of 14 Cases.Mycopathologia · 2020Article
- Expert consensus-based clinical practice guidelines management of intravascular catheters in the intensive care unit.Annals of intensive care · 2020Review
- Impact of Infectious Disease Consultation in Patients With Candidemia: A Retrospective Study, Systematic Literature Review, and Meta-analysis.Open forum infectious diseases · 2020Article
- Risk factors predicting Candida infective endocarditis in patients with candidemia.Medical mycology · 2020Article
- Efficacy of a "Checklist" Intervention Bundle on the Clinical Outcome of Patients with Candida Bloodstream Infections: A Quasi-Experimental Pre-Post Study.Infectious diseases and therapy · 2020Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Most current guidelines do not recommend systematic screening with echocardiography in patients with candidemia, as Candida infective endocarditis (CIE) is considered an uncommon disease. During the study period, we recommended echocardiography systematically to all candidemic patients that did not have contraindications and accepted to participate in the study. We intended to assess the incidence of unrecognized CIE in adult patients with candidemia. Our institution is a tertiary teaching hospital in which we follow all patients with candidemia. From January 2007 to October 2012, echocardiography was systematically recommended to suitable candidates. We recorded 263 cases of candidemia in adult patients. Echocardiography was not performed in 76 of these patients for the following reasons: patients had died when blood cultures became positive (17), patients were critically or terminally ill (38), or the patient or physician refused the procedure (21). The remaining 187 patients constitute the basis of this report. CIE was diagnosed in 11 cases (4.2 % of the whole candidemic population and 5.9 % of the population with echocardiographic study). The results of transthoracic echocardiography (TTE) suggested infective endocarditis (IE) in 5/172 patients (2.9 %), and the result of transesophageal echocardiography (TEE) was positive in 10/87 (11.5 %). Among 11 confirmed cases of CIE, the disease was clinically unsuspected in three patients. At least 4.2 % of all candidemic patients have CIE. CIE is frequently clinically unsuspected and echocardiography is required to demonstrate a high proportion of cases.
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