ArticleJournal of medical virology2015
Atypical presentation of human bocavirus: Severe respiratory tract infection complicated with encephalopathy.
Article in Journal of medical virology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Atypical causes of respiratory virus infections in Sub-Saharan Africa from 2013- 2023: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Twenty years of human bocavirus research: from an unculturable virus of unclear pathogenicity to a culturable human pathogen and gene therapy vector candidate.Clinical microbiology reviews · 2025Review
- Human bocavirus-1 infection in hospitalized pediatric patients with acute respiratory tract infections.Microbiology spectrum · 2025Article
- Life-Threatening Conditions in Children with Bocavirus Infection-Case Series and Mini Review of the Literature.Viruses · 2024Review
- Neurological Impact of Respiratory Viruses: Insights into Glial Cell Responses in the Central Nervous System.Microorganisms · 2024Review
- Analysis of a Cohort of 165 Pediatric Patients with Human Bocavirus Infection and Comparison between Mono-Infection and Respiratory Co-Infections: A Retrospective Study.Pathogens (Basel, Switzerland) · 2024Article
- Prevalence and significance of a canine bocavirus-2 outbreak in a cohort of military dogs in Austria.Frontiers in veterinary science · 2024Article
- Carnivore chaphamaparvovirus-1 (CaChPV-1) infection in diarrheic dogs reveals viral endotheliotropism in intestine and lung.The veterinary quarterly · 2023Article
- Human Bocavirus in Childhood: A True Respiratory Pathogen or a "Passenger" Virus? A Comprehensive Review.Microorganisms · 2023Review
- Acute encephalopathy with biphasic seizures and late restricted diffusion temporally associated with human bocavirus infection.BMJ case reports · 2022Article
- Epidemiology of Human Bocavirus in the Middle East and North Africa: Systematic Review.Pathogens (Basel, Switzerland) · 2021Review
- Occurrence and risk factors associated with seizures in infants with severe bronchiolitis.European journal of pediatrics · 2021Article
- Seasonal Coronaviruses and Other Neglected Respiratory Viruses: A Global Perspective and a Local Snapshot.Frontiers in public health · 2021Review
- Human bocavirus 1 respiratory tract reactivations or reinfections in two adults, contributing to neurological deficits and death.Access microbiology · 2021Article
- Canine bocavirus-2 infection and its possible association with encephalopathy in domestic dogs.PloS one · 2021Article
- Human Parvoviruses May Affect the Development and Clinical Course of Meningitis and Meningoencephalitis.Brain sciences · 2020Article
- Human bocavirus infection in Belgian children with respiratory tract disease.Archives of virology · 2019Article
- Acute necrotizing encephalopathy causing human bocavirus.The neuroradiology journal · 2017Article
- Frequent Detection and Genetic Diversity of Human Bocavirus in Urban Sewage Samples.Food and environmental virology · 2016Article
- Case Report: Human Bocavirus Associated Pneumonia as Cause of Acute Injury, Cologne, Germany.Medicine · 2015Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human bocavirus (HBOV) has been reported as a worldwide distributed respiratory pathogen. It has also been associated with encephalitis recently by detection of the virus in cerebrospinal fluid (CSF) of patients presented with encephalitis. This retrospective study aimed to present clinical features of HBOV infections in children with respiratory symptoms and describe unexplained encephalopathy in a subgroup of these patients. Results of 1,143 pediatric nasal samples from mid-December 2013 to July 2014 were reviewed for detection of HBOV. A multiplex real time polymerase chain reaction assay was used for viral detection. Medical records of the patients were retrospectively analyzed. HBOV was detected in 30 patients (2.6%). Median age was 14 months (5-80). Clinical diagnoses were upper respiratory tract infection (n = 10), bronchopneumonia (n = 9), acute bronchiolitis (n = 5), pneumonia (n = 4), acute bronchitis (n = 1), and asthma execarbation (n = 1). Hospitalization was required in 16 (53.3%) patients and 10 (62.5%) of them admitted to pediatric intensive care unit (PICU). Noninvasive mechanical ventilation modalities was applied to four patients and mechanical ventilation to four patients. Intractable seizures developed in four patients while mechanically ventilated on the 2nd-3rd days of PICU admission. No specific reason for encephalopathy was found after a thorough investigation. No mortality was observed, but two patients were discharged with neurological sequela. HBOV may lead to respiratory infections in a wide spectrum of severity. This report indicates its potential to cause severe respiratory infections requiring PICU admission and highlights possible clinical association of HBOV and encephalopathy, which developed during severe respiratory infection.
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