Evidence map›Paper›PMID 25966804›Full record

SynthesisInternational urogynecology journal2015

Risk factors for pelvic organ prolapse and its recurrence: a systematic review.

Tineke F M Vergeldt, Mirjam Weemhoff, Joanna IntHout, Kirsten B Kluivers

2 registry-linked trialsOpen access · hybridAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in International urogynecology journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 242 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
242citing papers in PubMed, 14 pooled it
23.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05918367 recruitingnot on this mapstarted 2023, after this paper: background citation

Multicenter Ventral Mesh Rectopexy Registry Collaborative

Typeobservational_patient_registrySponsorUniversity Hospital, AntwerpRan2023 to 2032Enrolled200ConditionsPelvic Organ Prolapse, Rectocele, Enterocele, Rectal Prolapse
NCT06520722 completednot on this mapstarted 2023, after this paper: background citation

A New POP(Pelvic Organ Prolapse) Scoring System: Validity and Reliability

TypeobservationalSponsorCairo UniversityRan2023 to 2024Enrolled75ConditionsPelvic Organ Prolapse, Prolapse, Prolapse, Vaginal, Prolapse UterusArmsProlapse scoring system
3 · Its place in the literature

Who cites it

242 citing papers in PubMed, 14 syntheses or guidelines pooled it, 560 citations in OpenAlex.

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  4. Transvaginal mesh or grafts or native tissue repair for vaginal prolapse.The Cochrane database of systematic reviews · 2024
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182 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Tineke F M VergeldtDepartment of Obstetrics and Gynecology, Radboud University Medical Center, P.O. Box 9101, 6500, HB, Nijmegen, The Netherlands. tinekevergeldt@gmail.com.
Mirjam WeemhoffDepartment of Obstetrics and Gynecology, Atrium Medical Center Parkstad, Heerlen, The Netherlands.
Joanna IntHoutDepartment for Health Evidence, Radboud University Medical Center, Nijmegen, The Netherlands.
Kirsten B KluiversDepartment of Obstetrics and Gynecology, Radboud University Medical Center, P.O. Box 9101, 6500, HB, Nijmegen, The Netherlands.
Radboud University Nijmegen · NLAtrium Medisch Centrum Parkstad · NLRadboud University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisPelvic organ prolapse (POP) is a common condition with multifactorial etiology. The purpose of this systematic review was to provide an overview of literature on risk factors for POP and POP recurrence.

methodsPubMed and Embase were searched with "pelvic organ prolapse" combined with "recurrence" and combined with "risk factors," with Medical Subject Headings and Thesaurus terms and text words variations until 4 August 2014, without language or publication date restrictions. Only cohort or cross-sectional studies carried out in western developed countries containing multivariate analyses and with a definition of POP based on anatomical references were included. POP recurrence had to be defined as anatomical recurrence after native tissue repair without mesh. Follow-up after surgery should have been at least 1 year. Articles were excluded if POP was not a separate entity or if it was unclear whether the outcome was primary POP or recurrence.

resultsPubMed and Embase revealed 2,988 and 4,449 articles respectively. After preselection, 534 articles were independently evaluated by two researchers, of which 15 met the selection criteria. In 10 articles on primary POP, 30 risk factors were investigated. Parity, vaginal delivery, age, and body mass index (BMI) were significantly associated in at least two articles. In 5 articles on POP recurrence, 29 risk factors were investigated. Only preoperative stage was significantly associated in at least two articles.

conclusionParity, vaginal delivery, age, and BMI are risk factors for POP and preoperative stage is a risk factor for POP recurrence.

Indexed as

FemaleHumansPelvic Organ ProlapseRecurrenceRisk FactorsPelvic organ prolapseRecurrenceRisk factors

Identifiers

PMID25966804
PMCPMC4611001
OpenAlexW266284716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.