Evidence map›Paper›PMID 25966679›Full record

Trial reportKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2017

Periarticular injections with continuous perfusion of local anaesthetics provide better pain relief and better function compared to femoral and sciatic blocks after TKA: a randomized clinical trial.

A Stathellis, W Fitz, C Schnurr, F X Koeck, M Gebauer, J Huth, G Bauer, J Beckmann

Abstract readComparative StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 28 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. CORR InsightsClinical orthopaedics and related research · 2017
    Article
  10. [Peripheral nerve block and rebound pain: literature review].Brazilian journal of anesthesiology (Elsevier)
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

A StathellisDepartment for Endoprosthetics Lower Extremity and Foot Surgery, Sportklinik Stuttgart GmbH, Taubenheimstr. 8, 70372, Stuttgart, Germany.
W FitzBrigham and Women's Hospital, Boston, MA, USA.
C SchnurrSt. Vinzenz-Krankenhaus, Düsseldorf, Germany.
F X KoeckMedArtes Praxisklinik, Neutraubling, Germany.
M GebauerHELIOS ENDO-Klinik Hamburg, Hamburg, Germany.
J HuthDepartment for Endoprosthetics Lower Extremity and Foot Surgery, Sportklinik Stuttgart GmbH, Taubenheimstr. 8, 70372, Stuttgart, Germany.
G BauerDepartment for Endoprosthetics Lower Extremity and Foot Surgery, Sportklinik Stuttgart GmbH, Taubenheimstr. 8, 70372, Stuttgart, Germany.
J BeckmannDepartment for Endoprosthetics Lower Extremity and Foot Surgery, Sportklinik Stuttgart GmbH, Taubenheimstr. 8, 70372, Stuttgart, Germany. drjbeckmann@gmx.de.
Klinikum Stuttgart · DEBrigham and Women's Hospital · USHelios Endo-Klinik Hamburg · DEOrthopädische Praxis · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCombined femoral and sciatic nerve blocks for post-operative pain management following total knee arthroplasty (TKA) improve patient satisfaction, decrease narcotic consumption and improve pain. However, accompanying motoric weakness can cause falls and related complications. We wonder whether peri-capsular injections in combination with intra-articular perfusion of local anaesthetics would result in equal or less pain without the related complications of nerve blocks. The objective of the study was to verify these aspects in a prospective randomized trial comparing both treatments.

methodsFifty TKA patients randomly received either a femoral (continuous) and a sciatic (single-shot) nerve block (CFNB group, 25 knees) or periarticular infiltrations and a continuous post-operative intra-articular infusion (PIAC group, 25 knees). VAS for pain, pain medication consumption, functional assessment, straight leg raising as well as KSS were recorded post-operatively for 6 days.

resultsVAS (p < 0.001) and KSS (p = 0.05) were significantly better for PIAC. There was increased pain following CFNB compared to PIAC. Catheters stayed for 4 days, a pain 'rebound' occurred after removing in CFNB but not after PIAC. There was no difference in regard to knee function (n.s.), but straight leg raising was significant better following PIAC. There were two falls in patients with CFNB.

conclusionPeri-capsular injections combined with an intra-articular catheter provide better pain control, no rebound pain with better function and might decrease the risk of complications related to motor weakness. LEVEL OF EVIDENCE: I.

Indexed as

Arthroplasty, Replacement, KneeNerve BlockAgedAnesthetics, LocalDrug Administration ScheduleFemaleFemoral NerveFollow-Up StudiesHumansInfusions, ParenteralInjections, Intra-ArticularMaleMiddle AgedPain MeasurementPostoperative CarePostoperative PainAnesthetics, LocalInfiltrationIntra-articularLIANerve blockPeri-articularTKA

Identifiers

PMID25966679
OpenAlexW349797531

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.