Evidence map›Paper›PMID 25966630›Full record

ArticleEuropean journal of human genetics : EJHG2016

Ladakh, India: the land of high passes and genetic heterogeneity reveals a confluence of migrations.

Diane J Rowold, David Perez Benedico, Ralph Garcia-Bertrand, Shilpa Chennakrishnaiah, Miguel A Alfonso-Sanchez, Tenzin Gayden, Rene J Herrera

Abstract read
In one paragraph

Article in European journal of human genetics : EJHG, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Diane J RowoldFoundation for Applied Molecular Evolution, Gainesville, Florida, USA.
David Perez BenedicoDepartment of Biology, Miami Dade College, Miami, Florida, USA.
Ralph Garcia-BertrandDepartment of Molecular Biology, Colorado College, Colorado Springs, Colorado, USA.
Shilpa ChennakrishnaiahDepartment of Experimental Medicine, McGill University, Montreal, Quebec, Canada.
Miguel A Alfonso-SanchezDepartamento de Geńtica y Antropologıa Física, Facultad de Ciencia y Tecnologıa, Universidad del País Vasco (UPV/EHU), Bilbao, Spain.
Tenzin GaydenDepartment of Human Genetics, McGill University, Montreal, Quebec, Canada.
Rene J HerreraDepartment of Molecular Biology, Colorado College, Colorado Springs, Colorado, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Owing to its geographic location near the longitudinal center of Asia, Ladakh, the land of high passes, has witnessed numerous demographic movements during the past millenniums of occupation. In an effort to view Ladakh's multicultural history from a paternal genetic perspective, we performed a high-resolution Y-chromosomal survey of Ladakh, within the context of Y haplogroup and haplotype distributions of 41 Asian reference populations. The results of this investigation highlight the rich ethnic and genetic diversity of Ladkah which includes genetic contributions from disparate regions of the continent including, West, East, South and Central Asia. The phylogenetic signals from Ladakh are consistent with the Indo-Aryans' occupation during the Neolithic age and its historic connection with Tibet, as well as the East-West gene flow associated with the Silk Road.

Indexed as

Genetic HeterogeneityHuman MigrationChromosomes, Human, YGenetics, PopulationGenetic VariationHaplotypesHumansIndiaPhylogeographyTime Factors

Identifiers

PMID25966630
PMCPMC4755386

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.