Evidence map›Paper›PMID 25965404›Full record

SynthesisPloS one2015

Influence of uncomplicated phacoemulsification on central macular thickness in diabetic patients: a meta-analysis.

Jianping Liu, Richard Edward Jones, Jiangyue Zhao, Jinsong Zhang, Fan Zhang

Open access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Preoperative central macular thickness as a risk factor for pseudophakic macular edema.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021
    Article
  8. Article
  9. Article
  10. Article
  11. Macular changes after cataract surgery.Romanian journal of ophthalmology
    Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Jianping LiuDepartment of Ophthalmology, The Fourth Affiliated Hospital of China Medical University, Shenyang, Liaoning, People's Republic of China; Eye Hospital of China Medical University, Shenyang, Liaoning, People's Republic of China; Key Lens Research Laboratory of Liaoning Province, Shenyang, Liaoning, People's Republic of China.
Richard Edward JonesDepartment of Ophthalmology and Vision Science, University of Arizona College of Medicine, Tucson, Arizona, United States of America.
Jiangyue ZhaoDepartment of Ophthalmology, The Fourth Affiliated Hospital of China Medical University, Shenyang, Liaoning, People's Republic of China; Eye Hospital of China Medical University, Shenyang, Liaoning, People's Republic of China; Key Lens Research Laboratory of Liaoning Province, Shenyang, Liaoning, People's Republic of China.
Jinsong ZhangDepartment of Ophthalmology, The Fourth Affiliated Hospital of China Medical University, Shenyang, Liaoning, People's Republic of China; Eye Hospital of China Medical University, Shenyang, Liaoning, People's Republic of China; Key Lens Research Laboratory of Liaoning Province, Shenyang, Liaoning, People's Republic of China.
Fan ZhangDepartment of Ophthalmology, The Fourth Affiliated Hospital of China Medical University, Shenyang, Liaoning, People's Republic of China; Eye Hospital of China Medical University, Shenyang, Liaoning, People's Republic of China; Key Lens Research Laboratory of Liaoning Province, Shenyang, Liaoning, People's Republic of China.
Lens Technology (China) · CNFourth Affiliated Hospital of China Medical University · CNUniversity of Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the effect of uncomplicated phacoemulsification on central macular thickness (CMT) and best corrected visual acuity (BCVA) in both diabetic patients without diabetic retinopathy (DR) and diabetic patients with mild to moderate non-proliferative diabetic retinopathy (NPDR).

methodsPotential prospective observational studies were searched through PubMed and EMBASE. Standardized mean difference (SMD) and 95% confidence interval (CI) for changes in CMT and BCVA were evaluated at postoperative 1, 3 and 6 months. The pooled effect estimates were calculated in the use of a random-effects model.

resultsA total of 10 studies involving 190 eyes of diabetic patients without diabetic retinopathy and 143 eyes of diabetic patients with NPDR were identified. CMT values demonstrated a statistically significant increase after uncomplicated phacoemulsification at 1 month (SMD, -0.814; 95%CI, -1.230 to -0.399), 3 months (SMD, -0.565; 95%CI, -0.927 to -0.202) and 6 months (SMD, -0.458; 95%CI, -0.739 to -0.177) in diabetic patients with NPDR. There was no statistical difference in CMT values at postoperative 1 month (SMD, -1.206; 95%CI, -2.433 to 0.021)and no statistically significant increase in CMT values at postoperative3 months (SMD, -0.535; 95%CI, -1.252 to 0.182) and 6 months (SMD, -1.181; 95%CI, -2.625 to 0.263) in diabetic patients without DR.BCVA was significantly increased at postoperative 1 month (SMD, 1.149; 95%CI, 0.251 to 2.047; and SMD,1.349; 95%CI, 0.264 to 2.434, respectively) and 6 months (SMD, 1.295; 95%CI, 0.494 to 2.096; and SMD, 2.146; 95%CI, 0.172 to 4.120, respectively) in both diabetic patients without DR and diabetic patients with NPDR. Sensitivity analysis showed that the results were relatively stable and reliable.

conclusionUncomplicated phacoemulsification in diabetic patients with mild to moderate NPDR seemed to influence significantly the subclinical thickening of the macular zones at postoperative 1, 3 and 6 months compared with diabetic patients without DR. BCVA was significantly improved in both diabetic patients without DR and diabetic patients with mild to moderate NPDR.

Indexed as

PhacoemulsificationCataractDiabetes Mellitus, Type 2Diabetic RetinopathyEdemaHumansLens Implantation, IntraocularMacular EdemaProspective StudiesVisual Acuity

Identifiers

PMID25965404
PMCPMC4428827
OpenAlexW1921096064

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.