ReviewJournal of nephropathology2015
The role of Th1 and Th17 cells in glomerulonephritis.
Review in Journal of nephropathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 31 citations in OpenAlex.
- Rheumatoid arthritis exacerbates apical periodontitis in Wistar rats, increasing IL-17, TNF-α, TRAP, and RANKL levels.Odontology · 2026Article
- Novel T-cell subsets as non-invasive biomarkers of vascular damage along the predialysis stages of chronic kidney disease.Frontiers in medicine · 2024Article
- Blood MALT1, Th1, and Th17 cells are dysregulated, inter-correlated, and correlated with disease activity in rheumatoid arthritis patients; meanwhile, MALT1 decline during therapy relates to treatment outcome.Journal of clinical laboratory analysis · 2022Article
- Elucidate multidimensionality of type 1 diabetes mellitus heterogeneity by multifaceted information.Scientific reports · 2021Article
- The Pathogenesis of End-Stage Renal Disease from the Standpoint of the Theory of General Pathological Processes of Inflammation.International journal of molecular sciences · 2021Review
- Novel Immune Cell Subsets Exhibit Different Associations With Vascular Outcomes in Chronic Kidney Disease Patients-Identifying Potential Biomarkers.Frontiers in medicine · 2021Article
- From genes polymorphisms to mucosal expression of cytokines: evaluating IL-23/IL-17 axis in adult patients with gastritis.African health sciences · 2020Article
- Psoriasis-Like Inflammation Induced Renal Dysfunction through the TLR/NF-BioMed research international · 2020Article
- Autophagy enhances mesenchymal stem cell-mediated CD4Stem cell research & therapy · 2019Article
- Enhanced Th17 Responses in Patients with Autoimmune Hepatitis.Middle East journal of digestive diseases · 2019Article
- Low-dose IL-2 expands CD4Renal failure · 2018Article
- StabilizedJournal of immunology research · 2017Article
- CCL20 secreted from IgA1-stimulated human mesangial cells recruits inflammatory Th17 cells in IgA nephropathy.PloS one · 2017Article
- Association between IL17A and IL17F polymorphisms and risk of Henoch-Schonlein purpura in Chinese children.Rheumatology international · 2016Article
- The Changing Landscape of Renal Inflammation.Trends in molecular medicine · 2016Review
- Diabetes mellitus and renal failure: Prevention and management.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2015Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextT helper (Th) cells as an important part of the immune is responsible for elimination of invading pathogens. But, if Th cell responses are not regulated effectively, the autoimmune diseases might develop. The Th17 subset usually produces interleukin-17A which in experimental models of organ-specific autoimmune inflammation is very important. EVIDENCE ACQUISITIONS: Directory of open access journals (DOAJ), Google Scholar, Embase, Scopus, PubMed and Web of Science have been searched.
resultsFifty-six articles were found and searched. In the present review article, we tried to summarize the recently published data about characteristics and role of Th1 and Th17 cells and discuss in detail, the potential role of these T helpers immune responses in renal inflammation and renal injury, focusing on glomerulonephritis. Published papers in animal and human studies indicated that autoimmune diseases such as rheumatoid arthritis and multiple sclerosis, classically believed to be Th1-mediated, are mainly derived from a Th17 immune response. Identification of the Th17 subgroup has explained seemingly paradoxical observations and improved our understanding of immune-mediated inflammatory responses.
conclusionsSecretion of IL-17A, as well as IL-17F, IL-21, IL-22, suggests that Th17 subset may play a crucial role as a pleiotropic pro-inflammatory Th subset. There is experimental evidence to support the notion that Th1 and Th17 cells contribute to kidney injury in renal inflammatory diseases like glomerulonephritis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.