ArticleBMC cardiovascular disorders2015
Chronic hyperglycemia is associated with acute kidney injury in patients undergoing CABG surgery--a cohort study.
Article in BMC cardiovascular disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 46 citations in OpenAlex.
- Goal-directed multimodal analgesia to enhance recovery after coronary artery bypass grafting: a retrospective cohort study.Journal of cardiothoracic surgery · 2026Article
- Preoperative Glycemic Status in Elective Cardiac Surgery Procedures: HbA1c Independently Predicts Low Cardiac Output Syndrome and Mortality.Diagnostics (Basel, Switzerland) · 2026Article
- Risk factors and clinical outcome of postoperative hyperglycemia after cardiac surgery with cardiopulmonary bypass.Frontiers in cardiovascular medicine · 2025Article
- Risk Factors and Outcomes of Acute Kidney Injury After Cardiac Surgery: A Retrospective Observational Single-Center Study.Journal of clinical medicine research · 2024Article
- Association of HbA1c and utilization of internal mammary arteries with wound infections in CABG.Frontiers in cardiovascular medicine · 2024Article
- Role of necroptosis in kidney health and disease.Nature reviews. Nephrology · 2023Review
- Type 2 diabetes mellitus and In-hospital Major Adverse Cardiac and Cerebrovascular Events (MACCEs) and postoperative complications among patients undergoing on-pump isolated coronary artery bypass surgery in Northeastern Iran.BMC cardiovascular disorders · 2023Article
- Glycated haemoglobin and the risk of postoperative complications in people without diabetes: a prospective population-based study in UK Biobank.Anaesthesia · 2022Article
- Predictive Value of Glycosylated Hemoglobin for Post-operative Acute Kidney Injury in Non-cardiac Surgery Patients.Frontiers in medicine · 2022Article
- Intraoperative Hyperglycemia May Be Associated with an Increased Risk of Myocardial Injury after Non-Cardiac Surgery in Diabetic Patients.Journal of clinical medicine · 2021Article
- A novel nomogram to predict perioperative acute kidney injury following isolated coronary artery bypass grafting surgery with impaired left ventricular ejection fraction.BMC cardiovascular disorders · 2020Article
- Article
- The impact of diabetes mellitus on acute kidney injury after coronary artery bypass grafting.Journal of cardiothoracic surgery · 2020Observational
- The influence of glycemic status on the performance of cystatin C for acute kidney injury detection in the critically ill.Renal failure · 2019Observational
- Observational
- Chronic hyperglycemia with elevated glycated hemoglobin level and its association with postoperative acute kidney injury after a major laparoscopic abdominal surgery in diabetes patients.Journal of anesthesia · 2018Article
- The COMT-polymorphism is not associated with the incidence of acute kidney injury after cardiac surgery - a prospective cohort study.BMC nephrology · 2018Article
- Which factor is the most effective one in metabolic Sydrome on the outcomes after coronary artery bypass graft surgery? A cohort study of 5 Years.Journal of cardiothoracic surgery · 2018Article
- Haptoglobin 2-2 Phenotype Is Associated With Increased Acute Kidney Injury After Elective Cardiac Surgery in Patients With Diabetes Mellitus.Journal of the American Heart Association · 2017Article
- Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic hyperglycemia (CHG) with HbA1c as an indicator affects postoperative mortality and morbidity after coronary artery bypass grafting surgery (CABG). Acute kidney injury (AKI) is one of the frequent postoperative complications after CABG impacting short-and long-term outcomes. We investigated the association between CHG and postoperative incidence of AKI in CABG patients with and without history of diabetes mellitus (DM).
methodsThis cohort study consecutively enrolled patients undergoing CABG in 2009 at the department for cardiovascular surgery. CHG was defined as HbA1c ≥ 6.0%. Patients with advanced chronic kidney disease (CKD) were excluded. The incidence of postoperative AKI and its association with CHG was analyzed by univariate and multivariate logistic regression modeling.
resultsThree-hundred-seven patients were analyzed. The incidence of AKI was 48.2%. Patients with CHG (n = 165) were more likely to be female and had greater waist circumference as well as other comorbid conditions, such as smoking, history of DM, CKD, hypertension, pulmonary hypertension, and chronic obstructive pulmonary disease (all p ≤ 0.05). Preoperative eGFR, atrial fibrillation (AF), history of DM and CHG were associated with an increased risk of postoperative AKI in univariate analyses. In multivariate modelling, history of DM as well as preoperative eGFR and AF lost significance, while age, CHG and prolonged OP duration (p < 0.05) were independently associated with postoperative AKI.
conclusionsOur results suggest that CHG defined on a single measurement of HbA1c ≥ 6.0% was associated with the incidence of AKI after CABG. This finding might implicate that treatment decisions, including the selection of operative strategies, could be based on HbA1c measurement rather than on a recorded history of diabetes.
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