SynthesisInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2015
Improving global estimates of syphilis in pregnancy by diagnostic test type: A systematic review and meta-analysis.
Synthesis in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Trends and Predictors of Syphilis Prevalence in the General Population: Global Pooled Analyses of 1103 Prevalence Measures Including 136 Million Syphilis Tests.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Pooled it
- The Global Epidemiology of Syphilis in the Past Century - A Systematic Review Based on Antenatal Syphilis Prevalence.PLoS neglected tropical diseases · 2016Pooled it
- Pooled it
- Article
- Seroprevalence of syphilis and associated factors among pregnant women who attended antenatal care follow-up at public hospitals in Bahir Dar city, north-west Ethiopia: a cross-sectional study.BMJ public health · 2025Article
- Syphilis infection prevalence in the Middle East and North Africa: a systematic review and meta-analysis.EClinicalMedicine · 2024Article
- Sociodemographic and clinical characteristics associated with maternal and congenital syphilis - A prospective study in Peru.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2024Article
- Article
- WHO method for estimating congenital syphilis to inform surveillance and service provision, Paraguay.Bulletin of the World Health Organization · 2022Article
- Evaluating coverage of maternal syphilis screening and treatment within antenatal care to guide service improvements for prevention of congenital syphilis inJournal of global health · 2020Article
- A clinical audit of maternal syphilis in a regional hospital in KwaZulu-Natal, South Africa.Southern African journal of infectious diseases · 2020Article
- Better care for babies: the added value of a modified reverse syphilis testing algorithm for the treatment of congenital syphilis in a maternity Hospital in Central African Republic.BMC pediatrics · 2019Article
- Global burden of maternal and congenital syphilis and associated adverse birth outcomes-Estimates for 2016 and progress since 2012.PloS one · 2019Article
- Syphilis prevalence trends in adult women in 132 countries - estimations using the Spectrum Sexually Transmitted Infections model.Scientific reports · 2018Article
- High seroprevalence of syphilis infection among pregnant women in Yiregalem hospital southern Ethiopia.BMC infectious diseases · 2018Article
- Article
- Syphilis screening and treatment in pregnant women in Kinshasa, Democratic Republic of the Congo and in Lusaka, Zambia: a cross-sectional study.Gates open research · 2017Article
- Estimating prevalence trends in adult gonorrhoea and syphilis in low- and middle-income countries with the Spectrum-STI model: results for Zimbabwe and Morocco from 1995 to 2016.Sexually transmitted infections · 2017Article
- Strong associations between national prevalence of various STIs suggests sexual network connectivity is a common underpinning risk factor.BMC infectious diseases · 2017Article
- Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
background"Probable active syphilis," is defined as seroreactivity in both non-treponemal and treponemal tests. A correction factor of 65%, namely the proportion of pregnant women reactive in one syphilis test type that were likely reactive in the second, was applied to reported syphilis seropositivity data reported to WHO for global estimates of syphilis during pregnancy.
objectivesTo identify more accurate correction factors based on test type reported. SEARCH STRATEGY: Medline search using: "Syphilis [Mesh] and Pregnancy [Mesh]," "Syphilis [Mesh] and Prenatal Diagnosis [Mesh]," and "Syphilis [Mesh] and Antenatal [Keyword]. SELECTION CRITERIA: Eligible studies must have reported results for pregnant or puerperal women for both non-treponemal and treponemal serology. DATA COLLECTION AND ANALYSIS: We manually calculated the crude percent estimates of subjects with both reactive treponemal and reactive non-treponemal tests among subjects with reactive treponemal and among subjects with reactive non-treponemal tests. We summarized the percent estimates using random effects models. MAIN
resultsCountries reporting both reactive non-treponemal and reactive treponemal testing required no correction factor. Countries reporting non-treponemal testing or treponemal testing alone required a correction factor of 52.2% and 53.6%, respectively. Countries not reporting test type required a correction factor of 68.6%.
conclusionsFuture estimates should adjust reported maternal syphilis seropositivity by test type to ensure accuracy.
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