Evidence map›Paper›PMID 25963816›Full record

ReviewThe Journal of cell biology2015

Cytoskeletal dynamics: a view from the membrane.

Magdalena Bezanilla, Amy S Gladfelter, David R Kovar, Wei-Lih Lee

Abstract readReview
In one paragraph

Review in The Journal of cell biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

94 citing papers in PubMed.

  1. Heterotypic intercellular adhesion tunes efficiency of cell-on-cell migration.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  17. The role of the cytoskeleton in fibrotic diseases.Frontiers in cell and developmental biology · 2024
    Review
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  19. Article
  20. Review

34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Magdalena BezanillaDepartment of Biology, University of Massachusetts Amherst, Amherst, MA 01003 bezanilla@bio.umass.edu.
Amy S GladfelterDepartment of Biological Sciences, Dartmouth College, Hanover, NH 03755.
David R KovarDepartment of Molecular Genetics and Cell Biology and Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL 60637 Department of Molecular Genetics and Cell Biology and Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL 60637.
Wei-Lih LeeDepartment of Biology, University of Massachusetts Amherst, Amherst, MA 01003.

Funding

Mechanisms of Formin-Mediated Actin Filament Assembly - Renewal 01 - ResubmissionR01GM079265 · NIGMS · UNIVERSITY OF CHICAGO · PI KOVAR, DAVID R · 2007 to 2023
$4.5M
Mechanism of Dynein-Mediated Spindle PositioningR01GM076094 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI LEE, WEI-LIH · 2007 to 2016
$3.1M
NIGMS NIH HHS GM076094NIGMS NIH HHS GM079265NIGMS NIH HHS R01 GM076094NIGMS NIH HHS R01 GM079265
6 · The paper itself

Abstract

Many aspects of cytoskeletal assembly and dynamics can be recapitulated in vitro; yet, how the cytoskeleton integrates signals in vivo across cellular membranes is far less understood. Recent work has demonstrated that the membrane alone, or through membrane-associated proteins, can effect dynamic changes to the cytoskeleton, thereby impacting cell physiology. Having identified mechanistic links between membranes and the actin, microtubule, and septin cytoskeletons, these studies highlight the membrane's central role in coordinating these cytoskeletal systems to carry out essential processes, such as endocytosis, spindle positioning, and cellular compartmentalization.

Indexed as

Actin CytoskeletonAnimalsCell MembraneEndocytosisHumansMicrotubulesSeptinsSpindle ApparatusSeptins

Identifiers

PMID25963816
PMCPMC4427793

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.