Evidence map›Paper›PMID 25963295›Full record

Trial reportTrials2015

Efficacy and safety of electroacupuncture with different acupoints for chemotherapy-induced nausea and vomiting: study protocol for a randomized controlled trial.

Bo Chen, Shu-xiang Hu, Bao-hu Liu, Tian-yi Zhao, Bo Li, Yan Liu, Ming-yue Li, Xing-fang Pan, Yong-ming Guo, Ze-lin Chen and 1 more

Registry-linked trialOpen access · goldAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Trials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02195908 (The Comparative Study on the Effectiveness of Single Acupoint and Matching Acupoints.), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02195908 nacompletednot on this map

The Comparative Study on the Effectiveness of Single Acupoint and Matching Acupoints.

TypeinterventionalSponsorTianjin University of Traditional Chinese MedicineRan2014 to 2015Enrolled160Conditionsto Evaluate the Effectiveness of Acupucnture in the Management of Chemotherapy-induced Nausea and VomitingArmssingle point Neiguan(PC6) plus antiemetic drug, single point Zhongwan(CV12) plus antiemetic drug, matching points Neiguan(PC6) and Zhongwan(CV12) plus antiemetic drug, only antiemetic drug
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Electroacupuncture for Functional Constipation: A Multicenter, Randomized, Control Trial.Evidence-based complementary and alternative medicine : eCAM · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Bo ChenAcu-moxibustion and Tuina Department of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China. tjutcmchenbo@163.com.
Shu-xiang HuAcu-moxibustion and Tuina Department of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China. luanshijr@126.com.
Bao-hu LiuAcu-moxibustion and Tuina Department of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China. liubaohu2006@163.com.
Tian-yi ZhaoAcu-moxibustion and Tuina Department of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China. zhaotianyi89@126.com.
Bo LiAcu-moxibustion and Tuina Department of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China. bb2065402@163.com.
Yan LiuAcu-moxibustion and Tuina Department of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China. liuyantjbd@163.com.
Ming-yue LiClinical Practice Teaching Department of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China. limingyue7@163.com.
Xing-fang PanAcu-moxibustion and Tuina Department of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China. pangxingfang@163.com.
Yong-ming GuoAcu-moxibustion and Tuina Department of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China. Guoymxr@163.com.
Ze-lin ChenAcu-moxibustion and Tuina Department of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China. chenzelin328@163.com.
Yi GuoAcu-moxibustion and Tuina Department of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China. guoyi_168@163.com.
Tianjin University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMany patients experience nausea and vomiting during chemotherapy treatment. Evidence demonstrates that electroacupuncture is beneficial for controlling chemotherapy-induced nausea and vomiting (CINV). However, the acupoint or matching acupoint with the best efficacy for controlling CINV still remains unidentified. METHODS/

designThis study consists of a randomized controlled trial (RCT) with four parallel arms: a control group and three electroacupuncture groups (one with Neiguan (PC6), one with Zhongwan (CV12), and one with both PC6 and CV12). The control group received standard antiemetic only, while the other three groups received electroacupuncture stimulation with different acupoints besides the standard antiemetic. The intervention is done once daily from the first day (day 1) to the fourth day (day 4) during chemotherapy treatment. The primary outcome measures include frequency of nausea, vomiting and retching. The secondary outcome measures are the grade of constipation and diarrhea, electrogastrogram, assessment of quality of life, assessment of anxiety and depression, and other adverse effects during the chemotherapy. Assessments are scheduled from one day pre-chemotherapy (day 0) to the fifth day of chemotherapy (day 5). Follow-ups are done from day 6 to day 21. DISCUSSION: The aim of this study is to evaluate the efficacy and safety of electro-acupuncture with different acupoints in the management of CINV.

trial registrationThe register number of randomized controlled trial is NCT02195908 . The date of registration was 21 July 2014.

Indexed as

Acupuncture PointsAntiemeticsAntineoplastic AgentsClinical ProtocolsCombined Modality TherapyElectroacupunctureHumansNauseaQuality of LifeResearch DesignTime FactorsTreatment OutcomeVomitingAntiemeticsAntineoplastic Agents

Identifiers

PMID25963295
PMCPMC4445984
OpenAlexW2154386270

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.