Evidence map›Paper›PMID 25962945›Full record

ReviewCardiovascular journal of Africa

The burden of stroke in Africa: a glance at the present and a glimpse into the future.

Mayowa O Owolabi, Sally Akarolo-Anthony, Rufus Akinyemi, Donna Arnett, Mulugeta Gebregziabher, Carolyn Jenkins, Hemant Tiwari, Oyedunni Arulogun, Albert Akpalu, Fred Stephen Sarfo and 8 more

Registry-linked trialAbstract readReview
In one paragraph

Review in Cardiovascular journal of Africa. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04468945 (Effects of Mirror Therapy Versus Repetitive Facilitation Exercise on Upper Limb Function in Post-stroke Patient), which is not on this map. Cited by 245 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
245citing papers in PubMed, 14 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04468945 nacompletednot on this map

Effects of Mirror Therapy Versus Repetitive Facilitation Exercise on Upper Limb Function in Post-stroke Patient

TypeinterventionalSponsorRiphah International UniversityRan2019 to 2020Enrolled40ConditionsStroke PatientArmsmirror box therapy, Repetitive Facilitation Exercise
3 · Its place in the literature

Who cites it

245 citing papers in PubMed, 14 syntheses or guidelines pooled it.

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  6. Stroke in Africa: A systematic review and meta-analysis of the incidence and case-fatality rates.International journal of stroke : official journal of the International Stroke Society · 2023
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  11. Quality of life of stroke survivors in Africa: a systematic review and meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021
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185 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Mayowa O OwolabiCollege of Medicine, University of Ibadan and University College Hospital, Ibadan, Nigeria.
Sally Akarolo-AnthonyHarvard University, USA.
Rufus AkinyemiFederal Medical Centre, Abeokuta, Nigeria.
Donna ArnettUniversity of Alabama at Birmingham, USA.
Mulugeta GebregziabherMedical University of South Carolina, USA.
Carolyn JenkinsMedical University of South Carolina, USA.
Hemant TiwariUniversity of Alabama at Birmingham, USA.
Oyedunni ArulogunCollege of Medicine, University of Ibadan and University College Hospital, Ibadan, Nigeria.
Albert AkpaluUniversity of Ghana, Ghana.
Fred Stephen SarfoKwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Reginald ObiakoAhmadu Bello University, Zaria, Nigeria.
Lukman OwolabiBayero University, Kano, Nigeria.
Kwamena SagoeUniversity of Ghana, Ghana.
Sylvia MelikamCollege of Medicine, University of Ibadan and University College Hospital, Ibadan, Nigeria.
Abiodun M AdeoyeCollege of Medicine, University of Ibadan and University College Hospital, Ibadan, Nigeria.
Daniel LacklandMedical University of South Carolina, USA.
Bruce OvbiageleMedical University of South Carolina, USA.
Members of the H3Africa Consortium

Funding

Stroke Investigative Research & Educational Network (SIREN)U54HG007479 · NHGRI · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2013 to 2017
$4.2M
Tailored Hospital-based Risk Reduction to Impede Vascular Events after Stroke (THU01NS079179 · NINDS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI OVBIAGELE, BRUCE · 2012 to 2016
$2.1M
Improving neurologic outcome measurement for interventional research in IbadanR25NS080949 · NINDS · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI EPSTEIN, LEON G, OGUNNIYI, ADESOLA · 2012 to 2014
$811k
NHGRI NIH HHS U54 HG007479NINDS NIH HHS R25 NS080949NINDS NIH HHS U01 NS079179
6 · The paper itself

Abstract

objectiveInformation on the current burden of stroke in Africa is limited. The aim of this review was to comprehensively examine the current and projected burden of stroke in Africa.

methodsWe systematically reviewed the available literature (PubMed and AJOL) from January 1960 and June 2014 on stroke in Africa. Percentage change in age-adjusted stroke incidence, mortality and disability-adjusted life years (DALYs) for African countries between 1990 and 2010 were calculated from the Global Burden of Diseases (GBD) model-derived figures.

resultsCommunity-based studies revealed an age-standardised annual stroke incidence rate of up to 316 per 100,000 population, and age-standardised prevalence rates of up to 981 per 100,000. Model-based estimates showed significant mean increases in age-standardised stroke incidence. The peculiar factors responsible for the substantial disparities in incidence velocity, ischaemic stroke proportion, mean age and case fatality compared to high-income countries remain unknown.

conclusionsWhile the available study data and evidence are limited, the burden of stroke in Africa appears to be increasing.

Indexed as

Cost of IllnessQuality-Adjusted Life YearsAfricaAge FactorsGlobal HealthHumansIncidenceStroke

Identifiers

PMID25962945
PMCPMC4557491

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.