ArticleNeurosurgical review2015
Assessment of a method to determine deep brain stimulation targets using deterministic tractography in a navigation system.
Article in Neurosurgical review, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Alterations of White Matter Connectivity in Adults with Essential Hypertension.International journal of general medicine · 2024Trial
- Predicting Surgery Targets in Temporal Lobe Epilepsy through Structural Connectome Based Simulations.PLoS computational biology · 2015Trial
- Connectivity between the seizure onset zone and the thalamus correlates with seizure outcomes in thalamic responsive neurostimulation.Epilepsia · 2026Article
- Surgical Advances in Parkinson's Disease.Current neuropharmacology · 2024Review
- Connectivity-based segmentation of the thalamic motor region for deep brain stimulation in essential tremor: A comparison of deterministic and probabilistic tractography.NeuroImage. Clinical · 2024Article
- Connectivity-based parcellation of the amygdala and identification of its main white matter connections.Scientific reports · 2023Article
- Imaging Modalities Used for Frameless and Fiducial-Less Deep Brain Stimulation: A Single Centre Exploratory Study among Parkinson's Disease Cases.Diagnostics (Basel, Switzerland) · 2022Article
- Somatotopic Organization of Hyperdirect Pathway Projections From the Primary Motor Cortex in the Human Brain.Frontiers in neurology · 2022Article
- Variability of white matter anatomy in the subcallosal cingulate area.Human brain mapping · 2021Article
- The dentato-rubro-thalamic tract as the potential common deep brain stimulation target for tremor of various origin: an observational case series.Acta neurochirurgica · 2020Observational
- Thalamic Deep Brain Stimulation for Essential Tremor: Relation of the Dentatorubrothalamic Tract with Stimulation Parameters.World neurosurgery · 2020Article
- Targeting of the dentato-rubro-thalamic tract for MR-guided focused ultrasound treatment of essential tremor.The neuroradiology journal · 2019Article
- Using automated electrode localization to guide stimulation management in DBS.Annals of clinical and translational neurology · 2018Article
- Individualized parcellation of the subthalamic nucleus in patients with Parkinson's disease with 7T MRI.NeuroImage · 2018Article
- The potential value of probabilistic tractography-based for MR-guided focused ultrasound thalamotomy for essential tremor.NeuroImage. Clinical · 2018Article
- Using probabilistic tractography to target the subcallosal cingulate cortex in patients with treatment resistant depression.Psychiatry research. Neuroimaging · 2017Article
- Worsening of Verbal Fluency After Deep Brain Stimulation in Parkinson's Disease: A Focused Review.Computational and structural biotechnology journal · 2017Review
- Feasibility of Diffusion Tractography for the Reconstruction of Intra-Thalamic and Cerebello-Thalamic Targets for Functional Neurosurgery: A Multi-Vendor Pilot Study in Four Subjects.Frontiers in neuroanatomy · 2016Article
- Noise2Average: An iterative residual learning strategy for image denoising without clean data.Imaging neuroscience (Cambridge, Mass.)Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent advances in imaging permit radiologic identification of target structures for deep brain stimulation (DBS) for movement disorders. However, these methods cannot detect the internal subdivision and thus cannot determine the appropriate DBS target located within those subdivisions. The aim of this study is to provide a straightforward method to obtain an optimized target (OT) within DBS target nuclei using a widely available navigation system. We used T1- and T2-weighted images, fluid-attenuated inversion recovery (FLAIR) sequence, and diffusion tensor imaging (DTI) of nine patients operated for DBS in our center. Using the StealthViz® software, we segmented the targeted deep structures (subcortical targets) and the anatomically identifiable areas to which these target nuclei were connected (projection areas). We generated fiber tracts from the projection areas. By identifying their intersections with the subcortical targets, we obtained an OT within the DBS target nuclei. We computed the distances from the clinically effective electrode contacts (CEEC) to the OT obtained by our method and the targets provided by the atlas. These distances were compared using a Wilcoxon signed-rank test, with p < 0.05 considered statistically significant. We were able to identify OT coincident with the motor part of the subthalamic nucleus and the ventral intermediate nucleus. We clinically tested the results and found that the CEEC were significantly more closely related to the OT than with the targets obtained by the atlas. Our present results show that this novel method permits optimization of the stimulation site within the internal subdivisions of target nuclei for DBS.
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