ReviewZeitschrift fur Gerontologie und Geriatrie2015
Depression associated with dementia.
Review in Zeitschrift fur Gerontologie und Geriatrie, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.
- Effectiveness of Dance-Based Interventions on Depression for Persons With MCI and Dementia: A Systematic Review and Meta-Analysis.Frontiers in psychology · 2021Pooled it
- Stress Accelerates Depressive-Like Behavior through Increase of SPNS2 Expression in Tg2576 Mice.Biomolecules & therapeutics · 2025Article
- Age-specific associations between intergenerational support from children and depression in middle-aged and elderly Chinese: results from the China health and retirement longitudinal study.Frontiers in psychology · 2025Article
- Article
- Article
- Diagnostic disclosure of Alzheimer's disease in Brazil: a national survey of specialized physicians.Arquivos de neuro-psiquiatria · 2023Article
- Associations of Depressive Symptoms with Subjective Cognitive Decline in Elderly People-A Cross-Sectional Analysis from the AgeWell.de-Study.Journal of clinical medicine · 2023Article
- Indoleamine 2,3-Dioxygenase as a Therapeutic Target for Alzheimer's Disease and Geriatric Depression.Brain sciences · 2023Review
- Review
- Increased probability of mood disorders after age-related macular degeneration: a population-based cohort study.Scientific reports · 2022Article
- Central nervous system effects of 5-HTMolecular medicine (Cambridge, Mass.) · 2022Review
- Preventive Measures against the Development of Dementia in Old Age.Korean journal of family medicine · 2022Article
- Concordance of self- and informant-rated depressive symptoms in nursing home residents with Dementia: cross-sectional findings.BMC psychiatry · 2022Article
- Personalized Management and Treatment of Alzheimer's Disease.Life (Basel, Switzerland) · 2022Review
- Pharmacogenomics of Alzheimer's Disease: Novel Strategies for Drug Utilization and Development.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Effects of the FNDC5/Irisin on Elderly Dementia and Cognitive Impairment.Frontiers in aging neuroscience · 2022Review
- Towards a Consensus on Alzheimer's Disease Comorbidity?Journal of clinical medicine · 2021Review
- Depression in Alzheimer's Disease: A Delphi Consensus on Etiology, Risk Factors, and Clinical Management.Frontiers in psychiatry · 2021Article
- Review
- Predictors of Residential Care Admission in Community-Dwelling Older People With Dementia.Journal of the American Medical Directors Association · 2020Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Depression and cognitive disorders, including dementia and mild cognitive impairment, are common disorders in old age. Depression is frequent in dementia, causing distress, reducing the quality of life, exacerbating cognitive and functional impairment and increasing caregiver stress. Even mild levels of depression can significantly add to the functional impairment of dementia patients and the severity of psychopathological and neurological impairments increases with increasing severity of depression. Depressive symptoms may be both a risk factor for, as well as a prodrome of dementia. Major depressive syndrome of Alzheimer's disease may be among the most common mood disorders of older adults. Treating depression is therefore a key clinical priority to improve the quality of life both of people with dementia as well as their carergivers. Nonpharmacological approaches and watchful waiting should be attempted first in patients who present with mild to moderate depression and dementia. In cases of severe depression or depression not able to be managed through nonpharmacological means, antidepressant therapy should be considered.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.