Evidence map›Paper›PMID 25961893›Full record

ArticleThe Pediatric infectious disease journal2015

Association of White Blood Cell Count and C-Reactive Protein with Outcomes in Children Hospitalized for Community-acquired Pneumonia.

Derek J Williams, Matthew Hall, Katherine A Auger, Joel S Tieder, Karen E Jerardi, Mary Ann Queen, Angela M Statile, Angela L Myers, Samir S Shah

Abstract readMulticenter Study
In one paragraph

Article in The Pediatric infectious disease journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Factors Associated With Pneumonia Severity in Children: A Systematic Review.Journal of the Pediatric Infectious Diseases Society · 2018
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Potential Therapeutic Value of the STING Inhibitors.Molecules (Basel, Switzerland) · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Label-free hematology analysis using deep-ultraviolet microscopy.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Recent Developments in Pediatric Community-Acquired Pneumonia.Current infectious disease reports · 2016
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Derek J WilliamsFrom the *Division of Hospital Medicine, The Monroe Carell Jr. Children's Hospital at Vanderbilt, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee; †The Children's Hospital Association, Overland Park, Kansas; ‡Division of Hospital Medicine, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio; §Division of Hospital Medicine, Seattle Children's Hospital, Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington; and ¶Division of Hospital Medicine, Children's Mercy Hospital and Clinics, ‖Division of Infectious Diseases, Children's Mercy Hospital and Clinics, University of Missouri School of Medicine, Kansas City, Missouri.
Matthew Hall
Katherine A Auger
Joel S Tieder
Karen E Jerardi
Mary Ann Queen
Angela M Statile
Angela L Myers
Samir S Shah

Funding

Development and Validation of a Clinical Prediction Rule for Pediatric PneumoniaK23AI104779 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WILLIAMS, DEREK J. · 2013 to 2016
$688k
NIAID NIH HHS K23 AI104779NIAID NIH HHS K23AI104779
6 · The paper itself

Abstract

We examined the association between baseline peripheral white blood cell count and C-reactive protein (CRP) values with outcomes among 153 children hospitalized with pneumonia. In multivariable analyses, CRP, but not white blood cell count, was significantly associated with both fever duration and hospital length of stay. For every 1mg/dL increase in CRP, length of stay increased by 1 hour.

Indexed as

HospitalizationLeukocyte CountAdolescentChildChild, PreschoolCommunity-Acquired InfectionsC-Reactive ProteinFemaleFeverHumansInfantLength of StayMalePneumoniaRetrospective StudiesTreatment OutcomeC-Reactive Protein

Identifiers

PMID25961893
PMCPMC4654105

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.