Evidence map›Paper›PMID 25961844›Full record

ArticlePloS one2015

Cross-Sectional and Prospective Associations between Physical Activity and C-Reactive Protein in Males.

Aírton J Rombaldi, Lúcia C Pellanda, Renata M Bielemann, Denise P Gigante, Pedro C Hallal, Bernardo L Horta

Abstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aírton J RombaldiPost-Graduate Program in Physical Education. Federal University of Pelotas, Pelotas, Brazil.
Lúcia C PellandaFederal University of Health Sciences of Porto Alegre, Porto Alegre, Brazil; Institute of Cardiology of Rio Grande do Sul, Porto Alegre, Brazil.
Renata M BielemannPost-Graduate Program in Epidemiology. Federal University of Pelotas, Pelotas, Brazil.
Denise P GigantePost-Graduate Program in Epidemiology. Federal University of Pelotas, Pelotas, Brazil.
Pedro C HallalPost-Graduate Program in Physical Education. Federal University of Pelotas, Pelotas, Brazil; Post-Graduate Program in Epidemiology. Federal University of Pelotas, Pelotas, Brazil.
Bernardo L HortaPost-Graduate Program in Epidemiology. Federal University of Pelotas, Pelotas, Brazil.

Funding

Wellcome Trust 086974/Z/08/ZWellcome Trust 095582
6 · The paper itself

Abstract

backgroundThere is conflicting evidence about the association between physical activity and inflammatory markers. Few prospective studies are available, particularly from low and middle-income countries. This study was aimed at assessing the cross-sectional and prospective associations between physical activity and C-reactive protein (CRP) levels in males belonging to the 1982 Pelotas (Brazil) Birth Cohort Study.

methodsThe sample comprised 2,213 males followed up at the ages of 18 and 23 years. We performed high sensitivity CRP assays; we used a cut-off of 3 mg/L in categorical analyses. We measured physical activity by self-report at ages 18 and 23 years. Body mass index and waist circumference were studies as possible mediators.

resultsCRP levels above the 3mg/L cut-off were found in 13.3% (95%CI: 11.7; 14.8) of the individuals. We found no evidence for an association between physical activity (leisure-time or all-domains) and either continuous (geometrical mean) or categorical CRP. We confirmed these null findings in (a) prospective and cross-sectional analyses; (b) trajectories analyses.

conclusionsThere was no association between CRP levels and physical activity levels in early adulthood in a large birth cohort. Little variability in CRP at this early age is the likely explanation for these null findings.

Indexed as

Motor ActivityAdolescentAdultBiomarkersBody Mass IndexBrazilC-Reactive ProteinCross-Sectional StudiesFollow-Up StudiesHumansMaleProspective StudiesWaist CircumferenceYoung AdultBiomarkersC-Reactive Protein

Identifiers

PMID25961844
PMCPMC4427448

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.