ArticlePloS one2015
Intravoxel Incoherent Motion Diffusion Weighted MR Imaging at 3.0 T: Assessment of Steatohepatitis and Fibrosis Compared with Liver Biopsy in Type 2 Diabetic Patients.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Accuracy of Non-Invasive Imaging Techniques for the Diagnosis of MASH in Patients With MASLD: A Systematic Review.Liver international : official journal of the International Association for the Study of the Liver · 2025Pooled it
- Value of intravoxel incoherent motion in detecting and staging liver fibrosis: A meta-analysis.World journal of gastroenterology · 2020Pooled it
- Quantitative MR biomarkers in identifying steatohepatitis and fibrosis associated with metabolic dysfunction associated liver disease-a single center cross-sectional study.Abdominal radiology (New York) · 2026Article
- Prospective Comparison of DWI-Derived Virtual MR Elastography and Conventional MR Elastography in Metabolic Dysfunction-Associated Steatotic Liver Disease and Healthy Volunteers.Journal of magnetic resonance imaging : JMRI · 2026Article
- Reproducibility and Repeatability of Intravoxel Incoherent Motion MRI Acquisition Methods in Liver.Journal of magnetic resonance imaging : JMRI · 2024Article
- Monoexponential and advanced diffusion-weighted imaging for hepatic fibrosis staging based on high inter-examiner reliability.Saudi medical journal · 2024Article
- Quantitative magnetic resonance imaging for chronic liver disease.The British journal of radiology · 2021Review
- Diffusion-weighted MRI of the liver: challenges and some solutions for the quantification of apparent diffusion coefficient and intravoxel incoherent motion.American journal of nuclear medicine and molecular imaging · 2021Review
- Magnetic Resonance imaging analysis of liver fibrosis and inflammation: overwhelming gray zones restrict clinical use.Abdominal radiology (New York) · 2020Review
- Magnetic resonance imaging for the assessment of pathological hepatic findings in nonalcoholic fatty liver disease.Journal of medical ultrasonics (2001) · 2020Review
- Higher cut-off values of non-invasive methods might be needed to detect moderate-to-severe steatosis in morbid obese patients: a pilot study.Scientific reports · 2020Article
- Quantified MRI and 25OH-VitD3 can be used as effective biomarkers for patients with neoadjuvant chemotherapy-induced liver injury in CRCLM?BMC cancer · 2020Observational
- Progress of intravoxel incoherent motion diffusion-weighted imaging in liver diseases.World journal of clinical cases · 2020Review
- Topics on quantitative liver magnetic resonance imaging.Quantitative imaging in medicine and surgery · 2019Review
- Accurate IVIM model-based liver lesion characterisation can be achieved with only three b-value DWI.European radiology · 2018Article
- Intravoxel Incoherent Motion (IVIM) Diffusion-Weighted Imaging (DWI) in Patients with Liver Dysfunction of Chronic Viral Hepatitis: Segmental Heterogeneity and Relationship with Child-Turcotte-Pugh Class at 3 Tesla.Gastroenterology research and practice · 2018Article
- Intravoxel Incoherent Motion Diffusion-weighted Imaging: Evaluation of the Differentiation of Solid Hepatic Lesions.Translational oncology · 2017Article
- Evaluation of hepatic fibrosis: a review from the society of abdominal radiology disease focus panel.Abdominal radiology (New York) · 2017Review
- Intravoxel incoherent motion model-based analysis of diffusion-weighted magnetic resonance imaging with 3OncoTargets and therapy · 2016Article
- Intravoxel incoherent motion: application in differentiation of hepatocellular carcinoma and focal nodular hyperplasia.Diagnostic and interventional radiology (Ankara, Turkey)Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the capability of intravoxel incoherent motion (IVIM) diffusion-weighted imaging (DWI) to assess steatohepatitis and fibrosis determined by histopathology in type 2 diabetic patients.
methodsFifty-nine type 2 diabetic patients (49 women, 10 men; mean age, 54 ± 9 years) were submitted to liver biopsy for the evaluation of non-alcoholic fatty liver disease (NAFLD) and underwent DWI on a 3.0T MR system using 10 b values. Institutional approval and patient consent were obtained. Pure molecular-based (D), perfusion-related (D*), and vascular fraction (f) were calculated using a double exponential model and least squares curve fitting. D, D*, and f were compared between patients with and without steatohepatitis and between patients with and without fibrosis. The variables were compared by using the Ranksum test and Student t-test.
resultsSteatohepatitis was observed in 22 patients and fibrosis in 16 patients. A lower D median (0.70 s/mm2 vs. 0.83 s/mm2, p<0.05) and a lower D* median (34.39 s/mm2 vs. 45.23 s/mm2, p<0.05) were observed among those with steatohepatitis. A lower D median (0.70 s/mm2 vs. 0.82 s/mm2, p<0.05) and a lower D* median (35.01 s/mm2 vs. 44.76 s/mm2, p=0.05) were also observed among those with fibrosis.
conclusionIVIM-DWI has the potential to aid in the characterization of steatohepatitis and fibrosis.
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