Evidence map›Paper›PMID 25961395›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2015

Underestimation of the True Specificity of the Urine Lipoarabinomannan Point-of-Care Diagnostic Assay for HIV-Associated Tuberculosis.

Stephen D Lawn, Andrew D Kerkhoff, Mark P Nicol, Graeme Meintjes

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Observational
  6. Article
  7. Review
  8. Article
  9. Article
  10. TB testing in HIV-positive patients prior to antiretroviral treatment.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Urine lipoarabinomannan as a marker for low-risk of NTM infection in the CF airway.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2020
    Article
  16. Observational
  17. Review
  18. Review
  19. Article
  20. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Stephen D Lawn*Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom †The Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa ‡George Washington University School of Medicine and Health Sciences, Washington, DC §Department of Global Health, Academic Medical Center, Amsterdam Institute for Global Health and Development, University of Amsterdam, Amsterdam, the Netherlands ‖Division of Medical Microbiology and Institute for Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa ¶National Health Laboratory Service, Groote Schuur Hospital, Cape Town, South Africa #Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa **Clinical Infectious Diseases Research Initiative, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa ††Department of Medicine, Imperial College, London, United Kingdom.
Andrew D Kerkhoff
Mark P Nicol
Graeme Meintjes

Funding

Medical Research Council MR/M007375/1Wellcome Trust 088590Wellcome Trust 098316Wellcome Trust 100714
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AIDS-Related Opportunistic InfectionsDiagnostic Tests, RoutineFemaleHIV InfectionsHumansLipopolysaccharidesMaleMass ScreeningTuberculosis, PulmonaryLipopolysaccharides

Identifiers

PMID25961395
PMCPMC4486367

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.