ArticlePloS one2015
Numerical Modeling of Intraventricular Flow during Diastole after Implantation of BMHV.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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Who cites it
8 citing papers in PubMed.
- Intracardiac flow dynamics in mitral regurgitation: state of the art.European heart journal. Imaging methods and practice · 2025Review
- Effect of left ventricular assist device on the hemodynamics of a patient-specific left heart.Medical & biological engineering & computing · 2022Article
- Hydrodynamic Noise of Pulsating Jets through Bileaflet Mechanical Mitral Valve.BioMed research international · 2020Article
- Application of Patient-Specific Computational Fluid Dynamics in Coronary and Intra-Cardiac Flow Simulations: Challenges and Opportunities.Frontiers in physiology · 2018Review
- Review of numerical methods for simulation of mechanical heart valves and the potential for blood clotting.Medical & biological engineering & computing · 2017Review
- Heart blood flow simulation: a perspective review.Biomedical engineering online · 2016Review
- Correcting motion in multiplanar cardiac magnetic resonance images.Biomedical engineering online · 2016Article
- Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This work presents a numerical simulation of intraventricular flow after the implantation of a bileaflet mechanical heart valve at the mitral position. The left ventricle was simplified conceptually as a truncated prolate spheroid and its motion was prescribed based on that of a healthy subject. The rigid leaflet rotation was driven by the transmitral flow and hence the leaflet dynamics were solved using fluid-structure interaction approach. The simulation results showed that the bileaflet mechanical heart valve at the mitral position behaved similarly to that at the aortic position. Sudden area expansion near the aortic root initiated a clockwise anterior vortex, and the continuous injection of flow through the orifice resulted in further growth of the anterior vortex during diastole, which dominated the intraventricular flow. This flow feature is beneficial to preserving the flow momentum and redirecting the blood flow towards the aortic valve. To the best of our knowledge, this is the first attempt to numerically model intraventricular flow with the mechanical heart valve incorporated at the mitral position using a fluid-structure interaction approach. This study facilitates future patient-specific studies.
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