Evidence map›Paper›PMID 25960935›Full record

ArticleOncoimmunology

Molecular mimicry of MAGE-A6 and

Lazar Vujanovic, Jian Shi, John M Kirkwood, Walter J Storkus, Lisa H Butterfield

Open access · goldAbstract read
In one paragraph

Article in Oncoimmunology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Peptide-based vaccine for cancer therapies.Frontiers in immunology · 2023
    Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. CD56Frontiers in immunology · 2019
    Article
  17. Article
  18. Review
  19. Respiratory virus-induced heterologous immunity: Part of the problem or part of the solution?Allergo Journal : interdisziplinare Zeitschrift fur Allergologie und Umweltmedizin : Organ der Deutschen Gesellschaft fur Allergie- und Immunitatsforschung · 2018
    Review
  20. Genetically engineered T cells for cancer immunotherapy.Signal transduction and targeted therapy
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lazar VujanovicUniversity of Pittsburgh Cancer Institute ; Pittsburgh, PA USA ; University of Pittsburgh School of Medicine; Department of Medicine ; Pittsburgh, PA USA.
Jian ShiUniversity of Pittsburgh Cancer Institute ; Pittsburgh, PA USA ; University of Pittsburgh School of Medicine; Department of Medicine ; Pittsburgh, PA USA.
John M KirkwoodUniversity of Pittsburgh Cancer Institute ; Pittsburgh, PA USA ; University of Pittsburgh School of Medicine; Department of Medicine ; Pittsburgh, PA USA.
Walter J StorkusUniversity of Pittsburgh Cancer Institute ; Pittsburgh, PA USA ; University of Pittsburgh School of Medicine; Department of Immunology ; Pittsburgh, PA USA ; University of Pittsburgh School of Medicine; Department of Dermatology ; Pittsburgh, PA USA.
Lisa H ButterfieldUniversity of Pittsburgh Cancer Institute ; Pittsburgh, PA USA ; University of Pittsburgh School of Medicine; Department of Medicine ; Pittsburgh, PA USA ; University of Pittsburgh School of Medicine; Department of Immunology ; Pittsburgh, PA USA ; University of Pittsburgh School of Medicine; Department of Surgery ; Pittsburgh, PA USA.
University of Pittsburgh · USUPMC Hillman Cancer Center · US

Funding

Combinational Immunotherapy Targeting the Melanoma-Associated VasculatureR01CA169118 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI STORKUS, WALTER J. · 2012 to 2016
$2.1M
NCI NIH HHS R01 CA169118
6 · The paper itself

Abstract

A promising vaccine strategy for the treatment of cancer involves the use of vaccines incorporating tumor antigen-derived synthetic peptides that can be coordinately recognized by specific CD4

Indexed as

AdV, recombinant adenoviral vectorAPC, antigen presenting cellCD8+ T-cellCTL, cytotoxic T lymphocyteEBV, Epstein-Barr virusepitope mimicFBS, fetal bovine serumHD, healthy donorHLA, human leukocyte antigenHPLC, high-performance liquid chromatographyiDC, immature dendritic cellsIVS, in vitro stimulationMACS, Magnetic-Activated Cell SortingMAGE-A6mDC, mature dendritic cellsmelanomaMOI, multiplicity of infectionMycoplasma penetransPBMC, peripheral blood mononuclear cellPFU, plaque forming unitsRT-PCR, reverse transcription polymerase chain reactionTAA, tumor associated antigenTCM, T cell mediaTCR, T-cell receptor

Identifiers

PMID25960935
PMCPMC4368152
OpenAlexW2037105201

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.