ArticleOman medical journal2015
Vitamin D Deficiency in Patients with Irritable Bowel Syndrome: Does it Exist?
Article in Oman medical journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 4 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 4 syntheses or guidelines pooled it, 53 citations in OpenAlex.
- Manifestations of the oral mucosa and salivary glands in irritable bowel syndrome and microscopic colitis - A systematic review.Acta odontologica Scandinavica · 2025Pooled it
- A systematic review and meta-analysis of diet and nutrient intake in adults with irritable bowel syndrome.Neurogastroenterology and motility · 2024Pooled it
- Pooled it
- Vitamin D status in irritable bowel syndrome and the impact of supplementation on symptoms: what do we know and what do we need to know?European journal of clinical nutrition · 2018Pooled it
- Vitamin D supplementation in adolescents with irritable bowel syndrome: Is it useful? A randomized controlled trial.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology AssociationTrial
- Correction of Vitamin D Deficiency Improves PTSD Symptoms in Gulf War Veterans.Brain sciences · 2025Article
- Screening of vitamin D deficiency in children with chronic functional constipation.Przeglad gastroenterologiczny · 2025Article
- Contemporary Perspectives on the Role of Vitamin D in Enhancing Gut Health and Its Implications for Preventing and Managing Intestinal Diseases.Nutrients · 2024Review
- Vitamin D Deficiency (VDD) and Benefits of Supplementation in Veterans with IBS-D.Diagnostics (Basel, Switzerland) · 2023Article
- Role of in vitamin D in irritable bowel syndrome.World journal of clinical cases · 2023Review
- Vitamin D may alleviate irritable bowel syndrome by modulating serotonin synthesis: a hypothesis based on recent literature.Frontiers in physiology · 2023Review
- Non-pharmacologic approaches to treatment of pediatric functional abdominal pain disorders.Frontiers in pediatrics · 2023Review
- Association between Serum Vitamin D and Irritable Bowel Syndrome Symptoms in a Sample of Adults.Nutrients · 2022Article
- The Relationship between Gastrointestinal Health, Micronutrient Concentrations, and Autoimmunity: A Focus on the Thyroid.Nutrients · 2022Review
- Biomolecules from Plant Wastes Potentially Relevant in the Management of Irritable Bowel Syndrome and Co-Occurring Symptomatology.Molecules (Basel, Switzerland) · 2022Review
- Effect of Application of Treadmill Training on Metabolic Control and Vitamin D Level in Saudi Patients with Type 2 Diabetes Mellitus.Computational and mathematical methods in medicine · 2022Article
- Low Vitamin D Levels in Patients with Irritable Bowel Syndrome of a Tertiary Care Hospital: A Descriptive Cross-sectional Study.JNMA; journal of the Nepal Medical Association · 2021Article
- The relationship between dietary intakes and prevalence of irritable bowel syndrome in adolescent girls: A cross-sectional study.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2021Article
- [Role of vitamin D in pediatric irritable bowel syndrome].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021Review
- Vitamin D Deficiency and Unclear Abdominal Pain in Patients from Low- and Middle-Income Countries.International journal of environmental research and public health · 2019Observational
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesVitamin D has been found to be strongly associated with many systemic disorders. There has been an augmented interest within the medical community in vitamin D, especially its deficiency, in various systemic disorders. Although the role of vitamin D deficiency in irritable bowel syndrome (IBS) has not yet been established, studies are underway to clearly establish its role in the disease. The objective of our study was to elucidate and establish the role of vitamin D deficiency in IBS patients compared to a healthy control group.
methodsThis study is a comparative case control study of vitamin D deficiency in patients with IBS diagnosed with ROME 3 criteria of classification (the third ROME foundation classification) to an age and gender matched healthy control group. The vitamin D level was measured in both cohorts for comparison and the results interpreted statistically. Sixty patients with IBS and 100 healthy individuals were included as test and control groups, respectively, in the study. The mean serum vitamin D level (nmol/L) of IBS patients was compared to the control group.
resultsVitamin D deficiency was detected in 49 patients (82%) in the IBS group and 31 patients (31%) in the control group. There was a statistically significant difference in the mean vitamin D level (p=0.025) between the IBS group and control group.
conclusionsOur study shows that vitamin D deficiency is highly prevalent in patients with IBS and these results seem to have therapeutic implications. Vitamin D supplementation could play a therapeutic role in the control of IBS.
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