ArticlePrzeglad gastroenterologiczny2015
Treatment of hypertriglyceridemia-induced acute pancreatitis with insulin.
Article in Przeglad gastroenterologiczny, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 80 citations in OpenAlex.
- Hypertriglyceridaemia-Associated Acute Pancreatitis: Pathophysiological Insights and Advances in Clinical Management.Biomedicines · 2026Review
- Potential influence of gut microbiota on the process of hypertriglyceridemia-aggravated acute pancreatitis.World journal of gastroenterology · 2026Review
- Case Report: Morphologically striking eruptive xanthomas with lobulated papules: a sentinel sign of severe metabolic dysregulation.Frontiers in endocrinology · 2026Article
- Reduced activity of two LPL C-terminal variants, p.Glu396Val and novel p.Trp417Cys: a clinical, biochemical and structural study.Frontiers in physiology · 2026Article
- Plasmapheresis in Acute Hypertriglyceridemia-Induced Pancreatitis-The PHIP-JuGa-Study.United European gastroenterology journal · 2025Article
- Low-Molecular-Weight Heparin Plus Insulin in Hypertriglyceridemic Acute Pancreatitis: A Randomized Clinical Trial.JAMA network open · 2025Article
- Diagnostic and therapeutic management of severe acute pancreatitis. Evidence based medicine (EBM) clinical practice guidelines.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2025Article
- Propofol, Triglycerides, and Acute Pancreatitis: A Multicenter Epidemiologic Analysis.Annals of the American Thoracic Society · 2025Observational
- Pseudohypertriglyceridemia in a Patient with Pancreatitis Without Evidence for Glycerol Kinase Deficiency: A Rare Case Report and Review of the Literature.Diseases (Basel, Switzerland) · 2025Article
- The effect of blood glucose levels on serum triglyceride clearance in patients with hyperlipidemic acute pancreatitis.Scientific reports · 2025Article
- Metabolic disturbances in acute pancreatitis: mechanisms and therapeutic implications.Frontiers in endocrinology · 2025Review
- Hyperlipidemic Abdominal Crisis: A Unique Presentation of Isolated Severe Hypertriglyceridemia.Cureus · 2025Article
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- Comparative analysis of therapeutic plasma exchange vs. standard management in hypertriglyceridemia-induced acute pancreatitis: triglyceride reduction and clinical outcomes.Irish journal of medical science · 2024Article
- Hypertriglyceridemia-Induced Acute Pancreatitis in Pregnancy: A Case Report in Anesthetic Management.Cureus · 2024Article
- Optimizing lipid control in Taiwanese diabetic patients: A collaborative consensus by the Diabetes Association of the Republic of China (Taiwan) and the Taiwanese Association of Diabetes Educators.Journal of diabetes investigation · 2024Article
- Evaluating the efficacy and timing of blood purification modalities in early-stage hyperlipidemic acute pancreatitis treatment.Lipids in health and disease · 2023Review
- Nutrient digestibility, ruminal fermentation, and blood metabolites of growing cattle-fed fermented cassava pulp with added flavoring agents.Journal of advanced veterinary and animal research · 2023Article
- Analysis of Intravenous Insulin Dosing Requirements for Treatment of Severe Hypertriglyceridemia.Hospital pharmacy · 2023Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionHypertriglyceridaemia (HT)-induced pancreatitis rarely occurs unless triglyceride levels exceed 1000 mg/dl. Hypertriglyceridaemia over 1,000 mg/dl can provoke acute pancreatitis (AP) and its persistence can worsen the clinical outcome. In contrast, a rapid decrease in triglyceride level is beneficial. Insulin-stimulated lipoprotein lipase is known to decrease serum triglyceride levels. However, their efficacy in HT-induced AP is not well documented.
aimTo present 12 cases of AP successfully treated by insulin administration. MATERIAL AND
methodsThree hundred and forty-three cases of AP were diagnosed at our clinic between 2005 and 2012. Twelve (3.5%) of these cases were HT-induced AP. Twelve patients who suffered HT-induced AP are reported. Initial blood triglyceride levels were above 1000 mg/dl. Besides the usual treatment of AP, insulin was administered intravenously in continuous infusion. The patients' medical records were retrospectively evaluated in this study.
resultsSerum triglyceride levels decreased to < 500 mg/dl within 2-3 days. No complications of treatment were seen and good clinical outcome was observed.
conclusionsOur results are compatible with the literature. Insulin may be used safely and effectively in HT-induced AP therapy. Administration of insulin is efficient when used to reduce triglyceride levels in patients with HT-induced AP.
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