ArticleCase reports in oncology
A case of swyer syndrome associated with advanced gonadal dysgerminoma involving long survival.
Article in Case reports in oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 24 citations in OpenAlex.
- Advanced-Stage Gonadal Dysgerminoma in a Patient With a Previous Diagnosis of Familial Swyer Syndrome: A Very Rare Genetic Entity.Case reports in medicine · 2026Article
- Clinical, Histological and Genetic Characterisation of a Disorder of Sexual Development in a Pygmy Goat.Animals : an open access journal from MDPI · 2025Article
- Swyer Syndrome: A diagnostic challenge.JBRA assisted reproduction · 2025Article
- Unanticipated diagnosis of Swyer syndrome: a case report.Annals of medicine and surgery (2012) · 2024Article
- Rare case of complete gonadal dysgenesis in a female patient with primary amenorrhea and a 46XY karyotype.Clinical case reports · 2024Article
- Late presentation of Swyer syndrome: A case report.Radiology case reports · 2023Article
- Swyer Syndrome Presenting as Dysgerminoma: A Case Report.Journal of the ASEAN Federation of Endocrine Societies · 2023Article
- Complete gonadal dysgenesis analysis in the population of Latvia: malignant outcomes and a review of literature.Medicine and pharmacy reports · 2022Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Swyer syndrome is caused by abnormal sex differentiation during the embryonic period, resulting in incomplete intrauterine masculinization and undifferentiated gonads. The current case report describes a patient with Swyer syndrome associated with stage 3 gonadal dysgerminoma who has survived for 23 years. At age 18, this patient sought assistance for primary amenorrhea from the Gynecological Services Department of the University of Brasília Hospital. A physical examination revealed that the patient was at Tanner stage 4 with respect to axillary hair, breasts, and pubic hair; she presented with a eutrophic vagina and a small cervix. She was treated with a combination of estrogens and progestogens to induce cycling. Approximately 4 years later, a complex tumor was found and resected; a histopathological analysis revealed that this tumor was a right adnexal dysgerminoma with peritoneal affection. The patient was also subjected to chemotherapy. Her follow-up has continued to the present time, with no signs of tumor recurrence. In conclusion, this report describes an extremely rare case in which Swyer syndrome was associated with ovarian dysgerminoma; relative to similar patients, the described patient has survived for an unusually prolonged time.
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