Evidence map›Paper›PMID 25960708›Full record

ArticleGynecological surgery

Cross-linked xenogenic collagen implantation in the sheep model for vaginal surgery.

Masayuki Endo, Iva Urbankova, Jaromir Vlacil, Siddarth Sengupta, Thomas Deprest, Bernd Klosterhalfen, Andrew Feola, Jan Deprest

Open access · hybridAbstract read
In one paragraph

Article in Gynecological surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Transvaginal Mesh Insertion in the Ovine Model.Journal of visualized experiments : JoVE · 2017
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Masayuki EndoCentre for Surgical Technologies, Faculty of Medicine, KU Leuven, Herestraat 49, 3000 Leuven, Belgium ; Department of Development and Regeneration, Organ Systems Cluster, Faculty of Medicine, KU Leuven, Herestraat 49, 3000 Leuven, Belgium ; Pelvic Floor Unit, University Hospitals KU Leuven, Leuven, Belgium.
Iva UrbankovaCentre for Surgical Technologies, Faculty of Medicine, KU Leuven, Herestraat 49, 3000 Leuven, Belgium ; Department of Development and Regeneration, Organ Systems Cluster, Faculty of Medicine, KU Leuven, Herestraat 49, 3000 Leuven, Belgium ; Institute for Care of Mother and Child, Prague, Czech Republic.
Jaromir VlacilCentre for Surgical Technologies, Faculty of Medicine, KU Leuven, Herestraat 49, 3000 Leuven, Belgium ; Department of Development and Regeneration, Organ Systems Cluster, Faculty of Medicine, KU Leuven, Herestraat 49, 3000 Leuven, Belgium ; Institute for Care of Mother and Child, Prague, Czech Republic.
Siddarth SenguptaDepartment of Development and Regeneration, Organ Systems Cluster, Faculty of Medicine, KU Leuven, Herestraat 49, 3000 Leuven, Belgium.
Thomas DeprestDepartment of Development and Regeneration, Organ Systems Cluster, Faculty of Medicine, KU Leuven, Herestraat 49, 3000 Leuven, Belgium.
Bernd KlosterhalfenInstitute for Pathology, Düren Hospital, Düren, Germany.
Andrew FeolaCentre for Surgical Technologies, Faculty of Medicine, KU Leuven, Herestraat 49, 3000 Leuven, Belgium ; Department of Development and Regeneration, Organ Systems Cluster, Faculty of Medicine, KU Leuven, Herestraat 49, 3000 Leuven, Belgium.
Jan DeprestCentre for Surgical Technologies, Faculty of Medicine, KU Leuven, Herestraat 49, 3000 Leuven, Belgium ; Department of Development and Regeneration, Organ Systems Cluster, Faculty of Medicine, KU Leuven, Herestraat 49, 3000 Leuven, Belgium ; Pelvic Floor Unit, University Hospitals KU Leuven, Leuven, Belgium.
Organ Recovery Systems (Belgium) · BEKU Leuven · BEKrankenhaus Düren · DEÚstav pro Péči o Matku a Dítě · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The properties of meshes used in reconstructive surgery affect the host response and biomechanical characteristics of the grafted tissue. Whereas durable synthetics induce a chronic inflammation, biological grafts are usually considered as more biocompatible. The location of implantation is another determinant of the host response: the vagina is a different environment with specific function and anatomy. Herein, we evaluated a cross-linked acellular collagen matrix (ACM), pretreated by the anti-calcification procedure ADAPT® in a sheep model for vaginal surgery. Ten sheep were implanted with a cross-linked ACM, and six controls were implanted with a polypropylene (PP; 56 g/m

Indexed as

Biological graftBiomechanicsContractilityGraft-related complicationProlapse

Identifiers

PMID25960708
PMCPMC4417472
OpenAlexW2091005633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.