Evidence map›Paper›PMID 25960645›Full record

ArticleClinical interventions in aging2015

Helicobacter pylori infection in Chinese patients with atrial fibrillation.

De-Zhao Wang, Wei Chen, Song Yang, Jun Wang, Qun Li, Qiang Fu, Shi-Jing Li, Bu-Xing Chen

Abstract read
In one paragraph

Article in Clinical interventions in aging, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Association between atrial fibrillation and Helicobacter pylori.Clinical research in cardiology : official journal of the German Cardiac Society · 2019
    Pooled it
  2. Pooled it
  3. Active Helicobacter pylori Infection and Atrial Fibrillation in Patients Hospitalized With Acute Myocardial Infarction.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2026
    Observational
  4. Article
  5. Metabolism open · 2025
    Review
  6. Reviews in cardiovascular medicine · 2025
    Review
  7. Research progress on the relationship betweenFrontiers in microbiology · 2025
    Review
  8. Review
  9. Relationship BetweenInternational journal of general medicine · 2021
    Review
  10. Article
  11. Review
  12. Evaluation ofChinese medical journal · 2017
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

De-Zhao WangDepartment of Cardiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, People's Republic of China.
Wei ChenDepartment of Cardiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, People's Republic of China.
Song YangDepartment of Ultrasonography, Beijing Tiantan Hospital, Capital Medical University, Beijing, People's Republic of China.
Jun WangDepartment of Cardiology, Beijing Mentougou District Hospital, Beijing, People's Republic of China.
Qun LiDepartment of Cardiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, People's Republic of China.
Qiang FuDepartment of Ultrasonography, Beijing Tiantan Hospital, Capital Medical University, Beijing, People's Republic of China.
Shi-Jing LiDepartment of Cardiology, Beijing Mentougou District Hospital, Beijing, People's Republic of China.
Bu-Xing ChenDepartment of Cardiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the relationship between Helicobacter pylori (Hp) infection and atrial fibrillation (AF) in Chinese patients.

methodsA total of 285 hospitalized patients with AF and 300 patients from Health Screening Center who matched age and sex with AF group were enrolled. AF patients were divided into two groups: the short-standing AF category (less than a year) and the long-standing AF category (more than a year). All patients had laboratory testing of (13)C urea breath test, high-sensitive C-reactive protein (hs-CRP) and left atrial diameter (LAD). We analyzed the difference of these factors in all groups and explored the correlation between Hp infection and AF using logistic regression analysis.

resultsBoth AF groups had more hypertension, diabetes, and Hp infection than the control group. The Hp value and the hs-CRP level in patients with long-standing AF were higher than those in the short-standing AF and the control groups (for Hp value: P<0.001 for both and for hs-CRP level: P=0.003, 0.002, respectively). The LAD of patients in the long-standing AF group was significantly larger than those in the short-standing AF group and control group (P=0.001 and P<0.001, respectively). The values of Hp, hs-CRP, and LAD in the long-standing AF category were significantly higher than those in the short-standing AF category (all P<0.05). After controlling the potential confounders, Hp value ≥4‰, hs-CRP >5 mg/L, and LAD >36 mm were significantly related to long-standing AF.

conclusionThe values of Hp in patients with long-standing AF were significantly higher than those in short-standing AF and control groups. Hp δ value ≥4‰ is an independent predictor for long-standing AF.

Indexed as

Asian PeopleAtrial FibrillationBreath TestsChinaC-Reactive ProteinDiabetes MellitusEchocardiographyFemaleHelicobacter InfectionsHelicobacter pyloriHumansHypertensionMalePredictive Value of TestsRetrospective StudiesTime FactorsC-Reactive Protein13C urea breath testhigh sensitivity C-reactive proteinleft atrial diameter

Identifiers

PMID25960645
PMCPMC4423503

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.