Evidence map›Paper›PMID 25960327›Full record

ArticleScientific reports2015

Variation in koala microbiomes within and between individuals: effect of body region and captivity status.

Niccoló Alfano, Alexandre Courtiol, Hanna Vielgrader, Peter Timms, Alfred L Roca, Alex D Greenwood

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 110 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. The Oral Microbiome in Queensland Free-Ranging Koalas (Animals : an open access journal from MDPI · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Gut Microbiome Profiling of the Endangered Southern Greater Glider (Animals : an open access journal from MDPI · 2023
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. A Peek into the Bacterial Microbiome of the Eurasian Red Squirrel (Animals : an open access journal from MDPI · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Niccoló AlfanoLeibniz Institute for Zoo and Wildlife Research, Berlin, Germany.
Alexandre CourtiolLeibniz Institute for Zoo and Wildlife Research, Berlin, Germany.
Hanna VielgraderTiergarten Schönbrunn, Vienna, Austria.
Peter TimmsUniversity of the Sunshine Coast, Sippy Downs, Queensland, Australia.
Alfred L RocaDepartment of Animal Sciences, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.
Alex D GreenwoodLeibniz Institute for Zoo and Wildlife Research, Berlin, Germany.
Leibniz Association · DELeibniz Institute for Zoo and Wildlife Research · DEUniversity of Illinois Urbana-Champaign · USUniversity of the Sunshine Coast · AU

Funding

A singular opportunity to determine the evolutionary genetics of retroviral invasR01GM092706 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI ROCA, ALFRED LUIS · 2011 to 2013
$849k
NIGMS NIH HHS R01 GM092706NIGMS NIH HHS R01GM092706
6 · The paper itself

Abstract

Metagenomic analysis of 16S ribosomal RNA has been used to profile microbial communities at high resolution, and to examine their association with host diet or diseases. We examined the oral and gut microbiome composition of two captive koalas to determine whether bacterial communities are unusual in this species, given that their diet consists almost exclusively of Eucalyptus leaves. Despite a highly specialized diet, koala oral and gut microbiomes were similar in composition to the microbiomes from the same body regions of other mammals. Rectal swabs contained all of the diversity present in faecal samples, along with additional taxa, suggesting that faecal bacterial communities may merely subsample the gut bacterial diversity. Furthermore, the faecal microbiomes of the captive koalas were similar to those reported for wild koalas, suggesting that captivity may not compromise koala microbial health. Since koalas frequently suffer from ocular diseases caused by Chlamydia infection, we also examined the eye microbiome composition of two captive koalas, establishing the healthy baseline for this body part. The eye microbial community was very diverse, similar to other mammalian ocular microbiomes but with an unusually high representation of bacteria from the family Phyllobacteriaceae.

Indexed as

Genetic VariationOrgan SpecificityAnimalsBacteriaEyeFecesGastrointestinal MicrobiomeMaleMicrobiotaMouthPhascolarctidaePhylogenyPrincipal Component AnalysisRectum

Identifiers

PMID25960327
PMCPMC4426690
OpenAlexW437742903

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.