ArticleNeuropsychologia2015
Differential contributions of hippocampus and medial prefrontal cortex to self-projection and self-referential processing.
Article in Neuropsychologia, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 1 of them a synthesis that pooled it.
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Who cites it
78 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Mindfulness in the focus of the neurosciences - The contribution of neuroimaging to the understanding of mindfulness.Frontiers in behavioral neuroscience · 2022Pooled it
- Intranasal oxytocin modulates the salience network in aging.NeuroImage · 2022Trial
- Contextual Modulation of Semantic Coherence in vmPFC Patients' Mental Constructions.Entropy (Basel, Switzerland) · 2026Article
- Scoping review of episodic future thinking and delay discounting observed in Alzheimer's disease, depression, and PTSD.Frontiers in psychology · 2026Review
- From single scenes to extended scenarios: The role of the ventromedial prefrontal cortex in the construction of imagery-rich events.PloS one · 2026Article
- When group grievances become personal: The neural correlates of group and personal rejection.Cognitive, affective & behavioral neuroscience · 2025Article
- Abnormal Synchronization Between Cortical Delta Power and Ripples in Hippocampal Sclerosis.Annals of clinical and translational neurology · 2025Article
- Self-referential belief shares common neural correlates with general belief.Scientific reports · 2025Article
- Missing images: autobiographical memory in Aphantasia and blindness.Frontiers in cognition · 2025Review
- Framing as a mechanism to overcome the temptation of bad habits.Frontiers in behavioral neuroscience · 2025Review
- Electroencephalography Oscillations During Prehypnosis and Hypnosis in Subjects With High and Low Dissociative Experiences.Basic and clinical neuroscience · 2025Article
- The human social cognitive network contains multiple regions within the amygdala.Science advances · 2024Article
- Taking time to compose thoughts with prefrontal schemata.Experimental brain research · 2024Article
- Social cognitive regions of human association cortex are selectively connected to the amygdala.bioRxiv : the preprint server for biology · 2024Article
- Development of the neural correlates of recollection.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- The Neural Signatures of Shame, Embarrassment, and Guilt: A Voxel-Based Meta-Analysis on Functional Neuroimaging Studies.Brain sciences · 2023Review
- Temporal Construal Effects Are Independent of Episodic Future Thought.Psychological science · 2023Article
- Functional specialization of parallel distributed networks revealed by analysis of trial-to-trial variation in processing demands.Journal of neurophysiology · 2023Article
- EEG Spatiotemporal Patterns Underlying Self-other Voice Discrimination.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- The thickness of the ventral medial prefrontal cortex predicts the prior-entry effect for allocentric representation in near space.Scientific reports · 2022Article
18 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors.
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Abstract
Converging evidence points to a neural network that supports a range of abilities including remembering the past, thinking about the future, and introspecting about oneself and others. Neuroimaging studies find hippocampal activation during event construction tasks, and patients with hippocampal amnesia are impaired in their ability to (re)construct events of the past and the future. Neuroimaging studies of constructed experiences similarly implicate the medial prefrontal cortex (mPFC), but it remains unknown whether the mPFC is critical for such processes. The current study compares performance of five patients with bilateral mPFC damage, six patients with bilateral hippocampal damage, and demographically matched comparison participants on an event construction task. Participants were given a neutral cue word and asked to (re)construct events across four time conditions: real past, imagined past, imagined present, and future. These event narratives were analyzed for the number of internal and external details to quantify the extent of episodic (re)experiencing. Given the literature on the involvement of the mPFC in self-referential processing, we also analyzed the event narratives for self-references. The patients with mPFC damage did not differ from healthy comparison participants in their ability to construct highly detailed episodic events across time periods but displayed disruptions in their incorporation of the self. Patients with hippocampal damage showed the opposite pattern; they were impaired in their ability to construct highly detailed episodic events across time periods but not in their incorporation of the self. The results suggest differential contributions of hippocampus and medial prefrontal cortex to the distributed neural network for various forms of self-projection.
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