Evidence map›Paper›PMID 25959101›Full record

ArticleScandinavian journal of gastroenterology2015

Liver transplantation in the Nordic countries - An intention to treat and post-transplant analysis from The Nordic Liver Transplant Registry 1982-2013.

Bjarte Fosby, Espen Melum, Kristian Bjøro, William Bennet, Allan Rasmussen, Ina Marie Andersen, Maria Castedal, Michael Olausson, Christina Wibeck, Mette Gotlieb and 20 more

Registry-linked trialAbstract readMulticenter Study
In one paragraph

Article in Scandinavian journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04161092 (A Randomized Controlled, Open-label, Multicentre Study Evaluating if Liver Transplantation With Liver Grafts From Extended Criteria Donors Not Utilised for Approved Indications Increases Overall Survival in Patients With Non-resectable Isolated Liver Metastases From Colorectal Metastases, in Comparison With Best Alternative Care), which is not on this map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04161092 naactive not recruitingnot on this mapstarted 2020, after this paper: background citation

A Randomized Controlled, Open-label, Multicentre Study Evaluating if Liver Transplantation With Liver Grafts From Extended Criteria Donors Not Utilised for Approved Indications Increases Overall Survival in Patients With Non-resectable Isolated Liver Metastases From Colorectal Metastases, in Comparison With Best Alternative Care

TypeinterventionalSponsorVastra Gotaland RegionRan2020 to 2030Enrolled45ConditionsColorectal Cancer, Liver Metastases, Colorectal Liver MetastasesArmsLiver transplantation Ltx, Best alternative care
3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Dietary Habits of Individuals With Primary Sclerosing Cholangitis-Poor Fat-Soluble Vitamin Intake and Dietary Quality.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Trial
  2. Review
  3. Review
  4. Outcome of Liver Retransplantation in Patients With Primary Sclerosing Cholangitis.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Article
  5. Article
  6. Total Robot-Assisted Minimally Invasive Esophagectomy for De Novo Esophageal Cancer after Liver Transplantation: The Potential of Robotic Surgery in a Complex Posttransplant Case.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2025
    Article
  7. Review
  8. Article
  9. The Spillover Effects of Extending Liver Transplantation to Patients with Colorectal Liver Metastases: A Discrete Event Simulation Analysis.Medical decision making : an international journal of the Society for Medical Decision Making · 2024
    Article
  10. Risk ofJournal of gastrointestinal oncology · 2024
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Liver transplant oncology: is it time to revisit our ideas?Hepatobiliary surgery and nutrition · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Bjarte FosbySection for Transplantation Surgery, Department of Transplantation Medicine, Division of Cancer, Surgery and Transplantation, Oslo University Hospital , Oslo , Norway.
Espen Melum
Kristian Bjøro
William Bennet
Allan Rasmussen
Ina Marie Andersen
Maria Castedal
Michael Olausson
Christina Wibeck
Mette Gotlieb
Henrik Gjertsen
Leena Toivonen
Stein Foss
Heikki Makisalo
Arno Nordin
Truls Sanengen
Annika Bergquist
Marie E Larsson
Gunnar Soderdahl
Greg Nowak
Kirsten Muri Boberg
Helena Isoniemi
Susanne Keiding
Aksel Foss
Pål-Dag Line
Styrbjörn Friman
Erik Schrumpf
Bo-Göran Ericzon
Krister Höckerstedt
Tom H Karlsen

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AIM AND

backgroundThe Nordic Liver Transplant Registry (NLTR) accounts for all liver transplants performed in the Nordic countries since the start of the transplant program in 1982. Due to short waiting times, donor liver allocation has been made without considerations of the model of end-stage liver disease (MELD) score. We aimed to summarize key outcome measures and developments for the activity up to December 2013. MATERIALS AND

methodsThe registry is integrated with the operational waiting-list and liver allocation system of Scandiatransplant (www.scandiatransplant.org) and accounted at the end of 2013 for 6019 patients out of whom 5198 were transplanted. Data for recipient and donor characteristics and relevant end-points retransplantation and death are manually curated on an annual basis to allow for statistical analysis and the annual report.

resultsPrimary sclerosing cholangitis, acute hepatic failure, alcoholic liver disease, primary biliary cirrhosis and hepatocellular carcinoma are the five most frequent diagnoses (accounting for 15.3%, 10.8%, 10.6%, 9.3% and 9.0% of all transplants, respectively). Median waiting time for non-urgent liver transplantation during the last 10-year period was 39 days. Outcome has improved over time, and for patients transplanted during 2004-2013, overall one-, five- and 10-year survival rates were 91%, 80% and 71%, respectively. In an intention-to-treat analysis, corresponding numbers during the same time period were 87%, 75% and 66%, respectively.

conclusionThe liver transplant program in the Nordic countries provides comparable outcomes to programs with a MELD-based donor liver allocation system. Unique features comprise the diagnostic spectrum, waiting times and the availability of an integrated waiting list and transplant registry (NLTR).

Indexed as

RegistriesWaiting ListsAdultAgedFemaleHumansIntention to Treat AnalysisKidney Failure, ChronicLiver TransplantationMaleMiddle AgedReoperationRetrospective StudiesScandinavian and Nordic CountriesSurvival RateTissue and Organ Procurementend-stage liver diseaseindicationliver transplantationorgan allocationoutcomeregistry

Identifiers

PMID25959101
PMCPMC4487534

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.