Evidence map›Paper›PMID 25958333›Full record

SynthesisRespiratory research2015

Sleep-disordered breathing and asthma: evidence from a large multicentric epidemiological study in China.

Liwen Li, Zhiwei Xu, Xingming Jin, Chonghuai Yan, Fan Jiang, Shilu Tong, Xiaoming Shen, Shenghui Li

Open access · goldAbstract readMeta-AnalysisMulticenter Study
In one paragraph

Synthesis in Respiratory research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Sleep disorders in children with asthma.Pediatric pulmonology · 2022
    Review
  6. Sex differences in the relationship of sleep-disordered breathing and asthma control among children with severe asthma.The Journal of asthma : official journal of the Association for the Care of Asthma · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Obstructive Sleep Apnea in Children and Adolescents and the Risk of Major Adverse Cardiovascular Events: A Nationwide Cohort Study in Taiwan.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2019
    Article
  13. Asthma and subjective sleep disordered breathing in a large cohort of urban adolescents.The Journal of asthma : official journal of the Association for the Care of Asthma · 2017
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Prevalence of Asthma and Sleep-Related Breathing Disorder in School-Going Children.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Liwen LiXin Hua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China. tiffanyli_sjtu@126.com.
Zhiwei XuSchool of Public Health and Social Work, Queensland University of Technology, Brisbane, Qld, Australia. xzw_xu@126.com.
Xingming JinChildren's Medical Center, School of Medicine, Shanghai Jiaotong University, Shanghai, China. zhujing7@sh163.net.
Chonghuai YanXin Hua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China. yanchk@gmail.com.
Fan JiangChildren's Medical Center, School of Medicine, Shanghai Jiaotong University, Shanghai, China. riversailer@sina.com.
Shilu TongSchool of Public Health and Social Work, Queensland University of Technology, Brisbane, Qld, Australia. s.tong@qut.edu.au.
Xiaoming ShenMOE - Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, 1665 Kong Jiang Road, Shanghai, 200092, China. shenxm9907@126.com.
Shenghui LiSchool of Public Health, Shanghai Jiao Tong University School of Medicine, 227 South Chongqing Road, Shanghai, 200127, PR China. Lsh9907@163.com.
Queensland University of Technology · AUShanghai Children's Medical Center · CNShanghai Jiao Tong University · CNXinHua Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious studies have postulated that sleep-disordered breathing (SDB) may be associated with the occurrence and exacerbation of asthma. However, there was limited quantitative evidence on the topic. This study aimed at investigating the prevalence and predisposing factors of asthma, and quantifying the association between SDB and asthma among school-aged children in China. In addition, a comprehensive meta-analysis of the published evidences and our findings were further conducted.

methodsTo test the hypothesis, we conducted a multicentric cross-sectional study involving 22,478 children aged 5-12 years recruited from eight cities in China. Furthermore, a meta-analysis based on both previously published studies and our cross-sectional study was performed.

resultsThe prevalence rate of SDB and asthma was 12.0% and 3.5% among our cross-sectional study sample. It was demonstrated that symptoms of SDB, such as habitual snoring (OR = 1.28, 95%CI: 1.01-1.62), and obstructive sleep apnea (OSA) (OR = 1.92, 95%CI: 1.34-2.76), were significantly associated with asthma, after adjusting for potential confounding factors. In the meta-analysis, SDB was correlated with the prevalence of asthma in both children (OR = 1.58, 95%CI: 1.35-1.80) and adults (OR = 1.55, 95%CI: 1.42-1.67).

conclusionsOur results provide further evidence for the independent association between SDB and asthma. The clinical significance of our findings lies in the emphasis that children undergoing examination or treatment for asthma should be routinely screened for sleep problems. Further systematic study is required to illuminate the underlying mechanism.

Indexed as

AsthmaCase-Control StudiesChildChild, PreschoolChinaCohort StudiesCross-Sectional StudiesFemaleHumansMaleSleep Apnea SyndromesSnoring

Identifiers

PMID25958333
PMCPMC4472264
OpenAlexW1571950254

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.