ReviewProgress in biophysics and molecular biology2015
Epigenetic mechanisms in schizophrenia.
Review in Progress in biophysics and molecular biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
34 citing papers in PubMed.
- Dysregulation of MiRNAs in schizophrenia in an Egyptian patient population.Scientific reports · 2025Article
- An In Vitro Study for the Role of Schizophrenia-Related Potential miRNAs in the Regulation of COMT Gene.Molecular neurobiology · 2024Article
- Implications of SNP-triggered miRNA dysregulation in Schizophrenia development.Frontiers in genetics · 2024Review
- Indicators of HSV1 Infection, ECM-Receptor Interaction, and Chromatin Modulation in a Nuclear Family with Schizophrenia.Journal of personalized medicine · 2023Article
- Review
- Genetic and psychosocial stressors have independent effects on the level of subclinical psychosis: findings from the multinational EU-GEI study.Epidemiology and psychiatric sciences · 2022Article
- Maternal High-Fat diet During Pregnancy and Lactation Disrupts NMDA Receptor Expression and Spatial Memory in the Offspring.Molecular neurobiology · 2022Article
- DNA Hypermethylation Induced by L-Methionine Leads to Oligodendroglial and Myelin Deficits and Schizophrenia-Like Behaviors in Adolescent Mice.Frontiers in neuroscience · 2021Article
- Effects of Cannabis Use on the Protein and Lipid Profile of Olfactory Neuroepithelium Cells from Schizophrenia Patients Studied by Synchrotron-Based FTIR Spectroscopy.Biomolecules · 2020Article
- Glutathione Deficiency and Alterations in the Sulfur Amino Acid Homeostasis during Early Postnatal Development as Potential Triggering Factors for Schizophrenia-Like Behavior in Adult Rats.Molecules (Basel, Switzerland) · 2019Article
- Mechanisms of Spontaneous Electrical Activity in the Developing Cerebral Cortex-Mouse Subplate Zone.Cerebral cortex (New York, N.Y. : 1991) · 2019Article
- Burden for Parents of Patients With Schizophrenia-A Nationwide Comparative Study of Parents of Offspring With Rheumatoid Arthritis, Multiple Sclerosis, Epilepsy, and Healthy Controls.Schizophrenia bulletin · 2019Article
- Effect of NMDA on proliferation and apoptosis in hippocampal neural stem cells treated with MK-801.Experimental and therapeutic medicine · 2018Article
- Non-Coding RNA as Novel Players in the Pathophysiology of Schizophrenia.Non-coding RNA · 2018Review
- An Update on Promising Biomarkers in Schizophrenia.Focus (American Psychiatric Publishing) · 2018Review
- Perceived Racial Discrimination and DNA Methylation Among African American Women in the InterGEN Study.Biological research for nursing · 2018Article
- DNA methylation in human diseases.Genes & diseases · 2018Review
- HDAC1 and HDAC3 underlie dynamic H3K9 acetylation during embryonic neurogenesis and in schizophrenia-like animals.Journal of cellular physiology · 2018Article
- Effects of Antipsychotic Drugs on the Epigenetic Modification of Brain-Derived Neurotrophic Factor Gene Expression in the Hippocampi of Chronic Restraint Stress Rats.Neural plasticity · 2018Article
- Maternal Diabetes and Fetal Programming Toward Neurological Diseases: Beyond Neural Tube Defects.Frontiers in endocrinology · 2018Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Epigenetic modifications, including DNA methylation, histone modifications, and non-coding RNAs, have been implicated in a number of complex diseases. Schizophrenia and other major psychiatric and neurodevelopmental disorders are associated with abnormalities in multiple epigenetic mechanisms, resulting in altered gene expression during development and adulthood. Polymorphisms and copy number variants in schizophrenia risk genes contribute to the high heritability of the disease, but environmental factors that lead to epigenetic modifications may either reduce or exacerbate the expression of molecular and behavioral phenotypes associated with schizophrenia and related disorders. In the present paper, we will review the current understanding of molecular dysregulation in schizophrenia, including disruption of the dopamine, NMDA, and GABA signaling pathways, and discuss the role of epigenetic factors underlying disease pathology.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.